Periciazine
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MedKoo CAT#: 525914

CAS#: 2622-26-6

Description: Periciazine is a drug that belongs to the phenothiazine class of typical antipsychotics. Periciazine is used to treat short-term severe anxiety or tension and in the maintenance treatment of psychotic disorders such as schizophrenia.

Chemical Structure

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Periciazine
CAS# 2622-26-6
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 525914
Name: Periciazine
CAS#: 2622-26-6
Chemical Formula: C21H23N3OS
Exact Mass: 365.16
Molecular Weight: 365.495
Elemental Analysis: C, 69.01; H, 6.34; N, 11.50; O, 4.38; S, 8.77

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25mg USD 450
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Synonym: Periciazine; Periciazine; Periciazinum; RP 8908; RP 8909; SKF 20,716.

IUPAC/Chemical Name: 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile

InChi Key: LUALIOATIOESLM-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2

SMILES Code: c1ccc2c(c1)N(c3cc(ccc3S2)C#N)CCCN4CCC(CC4)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
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Biological target: Pericyazine is a selective D2-dopamine receptor antagonist.
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 127.5 348.84

Preparing Stock Solutions

The following data is based on the product molecular weight 365.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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1: Nikolić K, Popović R. Conductometric determination of periciazine. Acta Pol Pharm. 1978;35(2):195-9. PubMed PMID: 27062.

2: Pedersen A. [Neulactil, M & B (Periciazine)]. Ugeskr Laeger. 1966 Sep 22;128(38):1131-3. Danish. PubMed PMID: 5981335.