LY 56110

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525551

CAS#: 26766-37-0

Description: LY 56110 is a novel class of nonsteroidal aromatase inhibitor.

Chemical Structure

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LY 56110
CAS# 26766-37-0
Instruction

Theoretical Analysis

MedKoo Cat#: 525551
Name: LY 56110
CAS#: 26766-37-0
Chemical Formula: C17H12Cl2N2
Exact Mass: 314.04
Molecular Weight: 315.200
Elemental Analysis: C, 64.78; H, 3.84; Cl, 22.49; N, 8.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: LY 56110; LY-56110; LY56110.

IUPAC/Chemical Name: Pyrimidine, 5-(bis(4-chlorophenyl)methyl)-

InChi Key: FOQIAMHLCXUKND-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H12Cl2N2/c18-15-5-1-12(2-6-15)17(14-9-20-11-21-10-14)13-3-7-16(19)8-4-13/h1-11,17H

SMILES Code: ClC1=CC=C(C(C2=CN=CN=C2)C3=CC=C(Cl)C=C3)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 315.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: O'Neill LA, Geisert RD, Zavy MT, Morgan GL, Wettemann RP. Effect of estrogen inhibitors on conceptus estrogen synthesis and development in the gilt. Domest Anim Endocrinol. 1991 Jan;8(1):139-53. PubMed PMID: 2013219.

2: Hirsch KS, Jones CD, Lindstrom TD, Stamm NB, Sutton GP, Taylor HM, Weaver DE. Discovery and development of a novel class of nonsteroidal aromatase inhibitors. Steroids. 1987 Jul-Sep;50(1-3):201-17. PubMed PMID: 3504060.

3: Lindstrom TD, Whitaker GW. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987 May;8(4):595-604. PubMed PMID: 3609545.