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571267
VU 0650786
VU 0650786 is a mGlu3 negative allosteric modulator. VU 0650786 has an mGlu2 IC50 ...
584952
VU 0650991
featured
VU 0650991 is a non-competitive GLP-1 antagonist that is orally bioavailable and a...
530334
VU0652925
VU0652925 is a PAR4 antagonist. VU0652925 had a PAC1 IC50 of 43.0 pM (-pIC50±SEM:...
532922
VU0661013
VU0661013 is a novel highly potent and specific inhibitor of myeloid cell leukemia...
532950
VU-1545
VU 1545 is a positive allosteric modulator of metabotropic glutamate receptor type...
555531
VU590 HCl
featured
VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM).
562002
VU591
featured
VU591 is the first reported selective, small-molecule ROMK inhibitor. It inhibits ...
571269
VU6001192
VU6001192 is a mGlu2 negative allosteric modulator
555331
VU6001376
VU6001376 is a potent and selective mGlu4 PAMs. It has EC50 = 50.1 nM, 50.5% GluMa...
571268
VU6001966
VU6001966 is a potent and selective mGlu2 inhibitor and Negative allosteric modula...
526000
VU6004256
VU6004256 is a novel selective muscarinic receptor M1 positive allosteric modulato...
463916
VU6004909
VU6004909 is a mGlu1 PAM.
530923
VU6005649
featured
VU6005649 is a potent and CNS Penetrant mGlu7/8 Receptor PAM with in vivo efficacy...
555316
VU6007477
VU6007477 is a novel M1 PAM. VU6007477 resulted in good rat M1 PAM potency (EC50 =...
564380
VU6007678
VU6007678 is a muscarinic acetylcholine receptor positive allosteric modulator (PAM).
564379
VU6007705
VU6007705 is a muscarinic acetylcholine receptor positive allosteric modulator (PAM).
564381
VU6008555
VU6008555 is a muscarinic acetylcholine receptor positive allosteric modulator (PAM).
563779
VU6009453
VU6009453 is a novel M4 positive allosteric modulator (PAM). VU6009453 showed good...
571266
VU 6010572
VU 6010572 is a negative allosteric modulator (NAM) for mGlu. VU 6010572 has an IC...
530983
VU6010608
VU6010608 is a potent mGlu7 NAM. VU6010608 showed excellent CNS penetration (Kp 1....
555413
VU6012962
featured
VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate recep...
463917
VU6013429
VU6013429 is a mGlu1 PAM.
593152
VU6015929
featured
VU6015929 is a selective discoidin domain receptor inhibitor. VU6015929 potently b...
533592
VU6015929 HCl
VU6015929 is a novel selective discoidin domain receptor 1/2 (DDR1/2) inhibitor, p...
533314
VU6017587
VU6017587 is a novel selective mGlu3 NAM, showing efficacy in tail suspension, ele...
562710
VU625
VU625 is a potent and selective inhibitor of aedes aegypti inward rectifier potass...
407936
VU661013
VU661013 is a MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistan...
561418
VU714 Oxalate
VU714 Oxalate is a novel Kir7.1 channel inhibitor. The inward rectifier potassium ...
564654
VU717
VU717 is a inhibitor of native Kir4.1 channels in astrocytes.
535142
VU-922
VU-922 is a bioactive chemical.
563959
VU937
VU937 is a negative control for VU041 (GLXC-11938), an inwardly rectifying potassi...
562619
VUF10132
VUF10132 is a full inverse agonist at CXCR3 N3.35A.
462861
VUF 10166
featured
VUF 10166 is an antagonist of the serotonin receptor subtype 5-HT3A. It is selecti...
555206
VUF-10214
VUF-10214 is a H4 receptor-ligand. In vivo studies in the rat reveal that VUF-1021...
555205
VUF-10214
VUF-10214 is a H4 receptor-ligand. In vivo studies in the rat reveal that VUF-1021...
555751
VUF10460
new
featured
VUF10460 is a histamine H4 receptor agonist.
555207
VUF-10497
VUF-10497 is a histamine H4 receptor inverse agonist (pKi = 7.57). VUF-10497 also ...
562240
VUF11211
VUF11211 is a potent CXCR3 antagonist. It acts by extending from the minor pocket ...
523101
VUF-11222
VUF-11222 is a high affinity non-peptide CXCR3 agonist (pKi = 7.2).
555418
VUF14480
VUF14480 is a covalent partial agonist that interacts with cysteine 98(3.36) of th...
555419
VUF14481
VUF14481 is a H4 receptor ligand.
563983
VUF14738
VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.
563984
VUF14862
VUF14862 is a robust and fatigue-resistant photoswitchable GPCR antagonist.
533435
VUF15888
VUF15888 is a novel photoswitchable modulator of the CXCR3 chemokine receptor.
558702
VUF16216
VUF16216 is a CXCR3 ligand which photoswitches from antagonism to agonism.
533436
VUF16620
VUF16620 is a novel photoswitchable modulator of the CXCR3 chemokine receptor.
465012
VUF16839
VUF16839 is a high-affinity non-imidazole histamine H3 receptor agonist.
533496
VUF16839 HCl
VUF16839 is a novel potent non-imidazole histamine H3 receptor agonist with in viv...
532951
VUF 4904
VUF 4904 is a bioactive chemical.
532952
VUF 5207
VUF 5207 is a bioactive chemical.
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