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Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential....
CAS#: 289480-64-4 (sodium)
Treprostinil is a vasodilator that is used for the treatment of pulmonary arterial hypertension. Treprostinil is a...
OF-1 is a chemical probe for BRPF bromodomains. OF-1 has been shown to bind to BRPF1B with a KD of 100 nM (ITC), to...
CAS#: 108392-02-5 (sodium)
DOPA lipid, also known as 18:1 PA; 1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt); PA(18:1(9Z)/18:1(9Z)); is a...
PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent...
Ochratoxin A (OTA) is a mycotoxin produced by several fungal species including Aspergillus ochraceus, A. carbonarius,...
O4I1 is a potent inducer of Oct3/4. O4I1 enhanced Oct3/4 expression. O4I1 not only promoted expression and...
Brincidofovir, also known as CMX001, HDP-CDV and HDPCDV, is DNA polymerase inhibitor potentially for the treatment of...
CAS#: 2349367-89-9 (free base)
NVS-ZP7-4 is a potent ZIP7 Inhibitor, which inhibits Notch signaling with IC50 of 0.13 uM in HES-Luc reporter gene...
NVS-PAK1-1 is a specific allosteric PAK1 inhibitor.
dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is...
NVP-BEP800, also known as BEP-800, is a novel, fully synthetic, orally bioavailable inhibitor that binds to the...
NV-5138 is an orally and centrally active small-molecule drug for the treatment of major depressive disorder (MDD)....
Davercin, also known as Erythromycin Cyclocarbonate, is a bacteriostatic antibiotic macrolide produced by...
BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PRMT5-RIOK1 complexes, and reduces...
NTP42 is a novel antagonist of the thromboxane prostanoid receptor (TP), currently in development for the treatment...
NTN21277, also known as Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and...
NSC-92828, also known as 3-Phenanthrenebutyric acid, is a Protein–protein interaction inhibitor (2P2 inhibitor or...
NSC77674, also known as Pyridoxal isonicotinoyl hydrazone and PIH is a lipophilic, nontoxic, iron-chelating agent...
NSC5844, also known as RE640, is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
NSC-45586 is a pan-PHLPP inhibitor selective for PHLPP1 and PHLPP2.
NSC348884 is a nucleophosmin inhibitor. NSC348884 also disrupts oligomer formation and induces apoptosis in human...
NSC-23026, also known as MSX-127, is a CXCR4 receptor modulator.
CYM 50308 is a novel agonist of SIP4 (EC50 = 56 nM) that displays 37-fold selectivity against S1P5 (EC50 = 2.1 μM)...
NS9283 is a positive allosteric modulator of α4β2 receptor. NS9283 increases the potency of Ach-evoked currents ~60...