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MS37452 is a modulator of methyl-lysine. It acts by inducing transcriptional derepression of p16/CDKN2A by disrupting...
NBI-31772 is an potent insulin-like growth factor-1 binding protein (IGFBP) inhibitor.
CTB ACT activator
Histone Acetyltransferase Activator, CTB, also referenced under CAS 451491-47-7, modulates the biological activity of...
Ro60-0175 free base
CAS#: 169675-08-5 (free base)
Ro60-0175 is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5,...
CAS#: 1287665-60-4 (HCl)
AS-2444697 is a RAK-4 inhibitor. Six weeks' repeated administration of AS2444697 (0.3-3 mg/kg, twice daily)...
FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1...
CAS#: 195156-77-5 (stearate)
Valomaciclovir stearate (A-174606.0; ABT-606; EPB-348; MIV-606; RP-606) is a DNA polymerase inhibitor potentially for...
BXT 51072, also known as ALT-2074, belongs to a class of drugs called "glutathione peroxidase mimics." BXT-51072...
TTK21 is an activator of CBP/p300 histone acetyltransferase activity.
Elimusertib free base
CAS#: 1876467-74-1 (free base)
Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor...
CAS#: 891016-02-7 (racemate)
ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium...
Obefazimod, also known as SPL-464 and ABX-464, is an inhibitor of the HIV replication potentially for the treatment...
SF1670 is a specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor. SF1670 specifically...
ML-148, also known as CID-3243760, is an inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH).
CAS#: PLX5622 hemifumarate
PLX5562 is a highly selective brain-penetrant CSF1R inhibitor. In the 5xFAD mouse model of AD, plaques fail to form...
CA77.1 is an activator of chaperone-mediated autophagy (CMA). CA77.1 activates chaperone-mediated autophagy (CMA) by...
Chromeceptin is an IGF2 inhibitor. Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process...
PQ-10 is a potent PDE-10 inhibitor. PQ-10 has >38-fold selectivity for PDE10 over a panel of 60 CNS-associated...
DMP-543, also known as XR-543, is a K-ATP channel blocker and acetylcholine release stimulator potentially for the...
Iptacopan free base
CAS#: 1644670-37-0 (free base)
Iptacopan, also known as LNP023, is a complement Factor B Inhibitor (IC50=10 nM). LNP023 improves LN in MRL/lpr mice....
WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. It reduces H3K14ac levels and inhibits growth and...
Primaquine is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P....
CKK-E12 is an ionizable lipid. It is useful for Development of Lipidoid Nanoparticles for siRNA, mRNA, and vaccine...
CAS#: 441045-17-6 (mesylate)
Eribulin is an anticancer drug marketed by Eisai Co. under the trade name Halaven. Eribulin is also known as E7389...
CAS#: 159857-79-1 (Val-cit-PAB-OH)
Val-cit-PAB-OH is an precursor for making MC-Val-Cit-PAB, which is also known as MC-Val-Cit-PAB-OH....