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EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabolite of losartan, produced by...
TES-1025 is the first potent and selective inhibitor of human ACMSD (IC50 = 0.013 μM) that increases NAD+ levels in...
WAY-647802 is a CDK inhibitor.
SR11237 is a pan retinoid X receptor (RXR) agonist. SR11237 destabilized the RXRα homodimer but promoted formation of...
HLY78 is an activator of the Wnt/β-Catenin signaling pathway. HLY78 protects blood-brain barrier integrity through...
BVT948 is a protein tyrosine phosphatases (PTP) inhibitor (IC50 = 0.09 - 1.7 μM). BVT948 inhibits NF-κB activation by...
SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50...
AAN06119 is a chemical reagent isolated from the leaves of the Indian plant Vitex negundo. It reduced the raw paw...
A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme with a K(i) of 1 nM...
A939572 is is a potent and orally bioavailable inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 value of 37nM....
A-804598 represents a structurally novel, competitive, and selective antagonist that has equivalent high affinity at...
CAS#: 1228013-15-7 (free base)
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with...
TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in...
YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).
Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin...
A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1...
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+...
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...
Lurbinectedin, also known as PM01183, is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid...
CAS#: 2310299-91-1 (citrate)
Gefapixant citrate is a P2X3 antagonist currently studied for use in the treatment of disorders associated with...
Nemtabrutinib , also known as ARQ-531 and MK-1026, is a potent and orally active BTK inhibitor with potential...
VX-150, also known as EOS-62073, is a pro-drug of a highly selective NaV1.8 inhibitor. VX-150 is an orally...
CAS#: 2101700-15-4 (S-isomer)
Pirtobrutinib, also known as LOXO-305 and LY 3527727, is a Bruton's tyrosine kinase (BTK) inhibitor and...
CAS#: 2192215-81-7 (tosylate)
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low...
CAS#: 22816-60-0 (HCl)
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant....