Newest Products

EXP-3174

CAT#: 522575
CAS#: 124750-92-1

EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabolite of losartan, produced by...

TES-1025

CAT#: 561896
CAS#: 1883602-21-8

TES-1025 is the first potent and selective inhibitor of human ACMSD (IC50 = 0.013 μM) that increases NAD+ levels in...

WAY-647802

CAT#: 556110
CAS#: 852225-20-8

WAY-647802 is a CDK inhibitor.

SR11237

CAT#: 526355
CAS#: 146670-40-8

SR11237 is a pan retinoid X receptor (RXR) agonist. SR11237 destabilized the RXRα homodimer but promoted formation of...

HLY78

CAT#: 556065
CAS#: 854847-61-3

HLY78 is an activator of the Wnt/β-Catenin signaling pathway. HLY78 protects blood-brain barrier integrity through...

BVT948

CAT#: 563502
CAS#: 39674-97-0

BVT948 is a protein tyrosine phosphatases (PTP) inhibitor (IC50 = 0.09 - 1.7 μM). BVT948 inhibits NF-κB activation by...

SB-265610

CAT#: 526278
CAS#: 211096-49-0

SB-265610 is a potent CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50...

AAN06119

CAT#: 555975
CAS#: 95906-11-9

AAN06119 is a chemical reagent isolated from the leaves of the Indian plant Vitex negundo. It reduced the raw paw...

A-966492

CAT#: 406362
CAS#: 934162-61-5

A-966492 is a potent PARP inhibitor, which displayed excellent potency against the PARP-1 enzyme with a K(i) of 1 nM...

A939572

CAT#: 526965
CAS#: 1032229-33-6

A939572 is is a potent and orally bioavailable inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 value of 37nM....

A-804598

CAT#: 530351
CAS#: 1125758-85-1

A-804598 represents a structurally novel, competitive, and selective antagonist that has equivalent high affinity at...

CC-115

CAT#: 205829
CAS#: 1228013-15-7 (free base)

CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with...

TLR2-IN-C29

CAT#: 562353
CAS#: 363600-92-4

TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in...

YKL-05-099

CAT#: 562115
CAS#: 1936529-65-5

YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).

Firategrast

CAT#: 319612
CAS#: 402567-16-2

Firategrast, also known as SB-683699 or T-0047, is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin...

A286982

CAT#: 531346
CAS#: 280749-17-9

A286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1...

A2793

CAT#: 556009
CAS#: 88349-90-0

A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+...

A-485

CAT#: 555116
CAS#: 1889279-16-6

A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and...

Lurbinectedin

CAT#: 581065
CAS#: 497871-47-3

Lurbinectedin, also known as PM01183, is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid...

Gefapixant citrate

CAT#: 575847
CAS#: 2310299-91-1 (citrate)

Gefapixant citrate is a P2X3 antagonist currently studied for use in the treatment of disorders associated with...

Nemtabrutinib

CAT#: 206974
CAS#: 2095393-15-8

Nemtabrutinib , also known as ARQ-531 and MK-1026, is a potent and orally active BTK inhibitor with potential...

VX-150

CAT#: 556330
CAS#: 1793080-72-4

VX-150, also known as EOS-62073, is a pro-drug of a highly selective NaV1.8 inhibitor. VX-150 is an orally...

Pirtobrutinib

CAT#: 465403
CAS#: 2101700-15-4 (S-isomer)

Pirtobrutinib, also known as LOXO-305 and LY 3527727, is a Bruton's tyrosine kinase (BTK) inhibitor and...

Ritlecitinib tosylate

CAT#: 585104
CAS#: 2192215-81-7 (tosylate)

Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low...

A22 hydrochloride

CAT#: 555259
CAS#: 22816-60-0 (HCl)

A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been shown to act as an antiobiotic adjuvant....