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MedKoo CAT#: 525737

CAS#: 195054-99-0

Description: NBI-30545 is a potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility used for stress disorders.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-12. Prices are subject to change without notice.

NBI-30545 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 525737
Name: NBI-30545
CAS#: 195054-99-0
Chemical Formula: C22H30N4O3
Exact Mass: 398.23179
Molecular Weight: 398.507
Elemental Analysis: C, 66.31; H, 7.59; N, 14.06; O, 12.04

Synonym: NBI-30545; NBI30545; NBI 30545

IUPAC/Chemical Name: 3-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)-2,5-dimethyl-N-propylpyrazolo[1,5-a]pyrimidin-7-amine


InChi Code: InChI=1S/C22H30N4O3/c1-7-10-25(11-12-27-4)20-13-15(2)23-22-21(16(3)24-26(20)22)18-9-8-17(28-5)14-19(18)29-6/h8-9,13-14H,7,10-12H2,1-6H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Chen C, Wilcoxen KM, Huang CQ, McCarthy JR, Chen T, Grigoriadis DE.
Optimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent
corticotropin-releasing factor-1 antagonists with adequate lipophilicity and
water solubility. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3669-73. PubMed PMID: