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MedKoo CAT#: 525725

CAS#: 1491-41-4

Description: Naftalofos is an insecticide and an anthelmintic. Naftalofos represents an effective therapeutic alternative for incorporation into worm control programmes.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 310 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-09. Prices are subject to change without notice.

Naftalofos, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 525725
Name: Naftalofos
CAS#: 1491-41-4
Chemical Formula: C16H16NO6P
Exact Mass: 349.07152
Molecular Weight: 349.27876
Elemental Analysis: C, 55.02; H, 4.62; N, 4.01; O, 27.48; P, 8.87

Synonym: Maretin; Naftalofosum; Naphthalophos; Rametin; Rawetin; Naftalofos

IUPAC/Chemical Name: 1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl diethyl phosphate


InChi Code: InChI=1S/C16H16NO6P/c1-3-21-24(20,22-4-2)23-17-15(18)12-9-5-7-11-8-6-10-13(14(11)12)16(17)19/h5-10H,3-4H2,1-2H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Kotze AC, Ruffell AP, Ingham AB. Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae. Antimicrob Agents Chemother. 2014 Dec;58(12):7475-83. doi: 10.1128/AAC.03333-14. Epub 2014 Oct 6. PubMed PMID: 25288079; PubMed Central PMCID: PMC4249576.
2: Fiel C, Guzmán M, Steffan P, Rodriguez E, Prieto O, Bhushan C. The efficacy of trichlorphon and naphthalophos against multiple anthelmintic-resistant nematodes of naturally infected sheep in Argentina. Parasitol Res. 2011 Aug;109 Suppl 1:S139-48. doi: 10.1007/s00436-011-2410-8. PubMed PMID: 21739383.
3: Kotze AC, Stein PA, Dobson RJ. Investigation of intestinal nematode responses to naphthalophos and pyrantel using a larval development assay. Int J Parasitol. 1999 Jul;29(7):1093-9. PubMed PMID: 10501619.
4: Cooper NA, Rolfe PF, Searson JE, Dawson KL. Naphthalophos combinations with benzimidazoles or levamisole as effective anthelmintics for sheep. Aust Vet J. 1996 Sep;74(3):221-4. PubMed PMID: 8894038.
5: Le Jambre LF, Barger IA. Efficiency of rafoxanide and naphthalophos against inhibited Haemonchus contortus. Aust Vet J. 1979 Jul;55(7):346-7. PubMed PMID: 518438.
6: Varshney TR, Singh YP. A comparative sutdy of anthelmintic effect of naphthalophos and parbendazole against natural infection of gastro-intestinal worms of sheep. Indian Vet J. 1979 Mar;56(3):207-10. PubMed PMID: 582588.
7: Leland SE Jr, Ridley RK, Dick JW, Slonka GF, Zimmerman GL. Anthelmintic activity of trichlorfon, coumaphos, and naphthalophos against the in vitro grown parastic stages of Cooperia punctata. J Parasitol. 1971 Dec;57(6):1190-6. PubMed PMID: 5157153.
8: Mullee MT, Cox DD, Allen AD. Effect of naphthalophos, phenothiazine, and thiabendazole on gastrointestinal nematode egg counts in feedlot cattle. Am J Vet Res. 1970 Jul;31(7):1203-15. PubMed PMID: 5447693.
9: Nelson DL, White RG, Mozier JO, Allen AD. Toxicity of larger-than-recommended doses of naphthalophos to cattle, sheep, and goats. Am J Vet Res. 1970 Jan;31(1):199-201. PubMed PMID: 5461126.
10: Partosoedjono S, Drudge JH, Lyons ET, Knapp FW. Evaluation of naphthalophos against Oestrus ovis and a thiabendazole-tolerant strain of Haemonchus contortus in lambs. Am J Vet Res. 1969 Jan;30(1):81-3. PubMed PMID: 5812440.
11: Train CT, White RG, Hansen MF. Efficacy of coumaphos and naphthalophos against nematodes of lambs. Am J Vet Res. 1968 Dec;29(12):2331-5. PubMed PMID: 5749116.
12: McDougald LR, White RG, Hansen MF. Efficacy of naphthalophos and coumaphos against nematodes of goats. Am J Vet Res. 1968 May;29(5):1077-9. PubMed PMID: 5646005.