Orders received during 11/25~11/29 will be shipped in 11/30/2020 due to Thanksgiving holiday.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526706

CAS#: 1473450-60-0

Description: NITD-304 is an antitubercular drug candidate for treating multidrug-resistant tuberculosis. NITD-304 showed potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb. Promising pharmacokinetic profiles of both compounds after oral dosing in several species enabled further evaluation for efficacy and safety. NITD-304 was efficacious in treating both acute and chronic Mtb infections in mouse efficacy models.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-11-25. Prices are subject to change without notice.

NITD-304 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526706
Name: NITD-304
CAS#: 1473450-60-0
Chemical Formula: C17H20Cl2N2O
Exact Mass: 338.0953
Molecular Weight: 339.26
Elemental Analysis: C, 60.19; H, 5.94; Cl, 20.90; N, 8.26; O, 4.72

Synonym: NITD-304; NITD 304; NITD304.

IUPAC/Chemical Name: 4,6-dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide


InChi Code: InChI=1S/C17H20Cl2N2O/c1-17(2)5-3-11(4-6-17)20-16(22)15-9-12-13(19)7-10(18)8-14(12)21-15/h7-9,11,21H,3-6H2,1-2H3,(H,20,22)

SMILES Code: O=C(C(N1)=CC2=C1C=C(Cl)C=C2Cl)NC3CCC(C)(C)CC3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Note: chemical structure was from
Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection
Jozef Stec, Oluseye K. Onajole, Shichun Lun, Haidan Guo, Benjamin Merenbloom, Giulio Vistoli, William R. Bishai, and Alan P. Kozikowski
Publication Date (Web): June 8, 2016 (Article)
DOI: 10.1021/acs.jmedchem.6b00415


1: Rao SP, Lakshminarayana SB, Kondreddi RR, Herve M, Camacho LR, Bifani P,
Kalapala SK, Jiricek J, Ma NL, Tan BH, Ng SH, Nanjundappa M, Ravindran S, Seah
PG, Thayalan P, Lim SH, Lee BH, Goh A, Barnes WS, Chen Z, Gagaring K, Chatterjee
AK, Pethe K, Kuhen K, Walker J, Feng G, Babu S, Zhang L, Blasco F, Beer D, Weaver
M, Dartois V, Glynne R, Dick T, Smith PW, Diagana TT, Manjunatha UH.
Indolcarboxamide is a preclinical candidate for treating multidrug-resistant
tuberculosis. Sci Transl Med. 2013 Dec 4;5(214):214ra168. doi:
10.1126/scitranslmed.3007355. PubMed PMID: 24307692.