WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526588

CAS#: 51022-73-2

Description: Zometapine is an antidepressant drug which is a pyrazolodiazepine derivative. Its molecular structure closely resembles benzodiazepines and is unrelated to other antidepressant drug classes.

Chemical Structure

CAS# 51022-73-2

Theoretical Analysis

MedKoo Cat#: 526588
Name: Zometapine
CAS#: 51022-73-2
Chemical Formula: C15H15FN4O
Exact Mass: 286.123
Molecular Weight: 286.3104
Elemental Analysis: C, 62.93; H, 5.28; F, 6.64; N, 19.57; O, 5.59

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: CI 716; CI-716; CI716; Zometapine; Zolazepamum; Flupyrazapon

IUPAC/Chemical Name: 4-(2-fluorophenyl)-1,3,8-trimethyl-6,8-dihydropyrazolo[3,4-e][1,4]diazepin-7(1H)-one


InChi Code: InChI=1S/C15H15FN4O/c1-9-13-14(10-6-4-5-7-11(10)16)17-8-12(21)19(2)15(13)20(3)18-9/h4-7H,8H2,1-3H3


Appearance: White to off-white solid powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 286.3104 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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1: Katz RJ. Effects of zometapine, a structurally novel antidepressant, in an animal model of depression. Pharmacol Biochem Behav. 1984 Oct;21(4):487-90. PubMed PMID: 6542226.

2: Fairchild CJ, Rush AJ, Vasavada N, Giles DE, Khatami M. Which depressions respond to placebo? Psychiatry Res. 1986 Jul;18(3):217-26. PubMed PMID: 3529150.