WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 526572
Description: WAY 150138 can cause the inhibition of the herpes simplex virus.
MedKoo Cat#: 526572
Name: WAY 150138
Chemical Formula: C22H18Cl2FN3O3S
Exact Mass: 493.043
Molecular Weight: 494.3624
Elemental Analysis: C, 53.45; H, 3.67; Cl, 14.34; F, 3.84; N, 8.50; O, 9.71; S, 6.49
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: WAY 150138; WAY150138; WAY-150138
IUPAC/Chemical Name: N-(3-chloro-4-(3-(5-chloro-2,4-dimethoxyphenyl)thioureido)phenyl)-2-fluorobenzamide
InChi Key: NPZHFWHOVNAVCF-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H18Cl2FN3O3S/c1-30-19-11-20(31-2)18(10-15(19)24)28-22(32)27-17-8-7-12(9-14(17)23)26-21(29)13-5-3-4-6-16(13)25/h3-11H,1-2H3,(H,26,29)(H2,27,28,32)
SMILES Code: O=C(NC1=CC=C(NC(NC2=CC(Cl)=C(OC)C=C2OC)=S)C(Cl)=C1)C3=CC=CC=C3F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 494.3624 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Newcomb WW, Brown JC. Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation. J Virol. 2002 Oct;76(19):10084-8. PubMed PMID: 12208991; PubMed Central PMCID: PMC136520.
2: Newcomb WW, Thomsen DR, Homa FL, Brown JC. Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids. J Virol. 2003 Sep;77(18):9862-71. PubMed PMID: 12941896; PubMed Central PMCID: PMC224603.
3: Pesola JM, Zhu J, Knipe DM, Coen DM. Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production. J Virol. 2005 Dec;79(23):14516-25. Erratum in: J Virol. 2006 Jun;80(12):6196. PubMed PMID: 16282451; PubMed Central PMCID: PMC1287588.