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MedKoo CAT#: 406767

CAS#: 1255143-82-8

Description: FY26 is a potent Os(II) anticancer drug candidate, exerts its activity by generating reactive oxygen species and disrupting the redox balance in cancer cells Coadministration of FY26 and nontoxic doses of L-BSO allows the potentiation of its anticancer activity, and most remarkably, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 is 49 times more potent than the clinically used treatment Cisplatin. FY26 is able to shut down a cancer cell by exploiting weaknesses inherent in their energy generation.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-06-02. Prices are subject to change without notice.

FY26 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 406767
Name: FY26
CAS#: 1255143-82-8
Chemical Formula: C23H28F6IN4OsP
Exact Mass:
Molecular Weight: 822.6037
Elemental Analysis: C, 33.58; H, 3.43; F, 13.86; I, 15.43; N, 6.81; Os, 23.13; P, 3.77

Related CAS #: 1255143-82-8   255143-81-7 (cation)    

Synonym: FY26; FY-26; FY 26.

IUPAC/Chemical Name: Osmium(1+)​, [N,​N-​dimethyl-​4-​[2-​(2-​pyridinyl-​κN)​diazenyl-​κN1]​benzenamine]​iodo[(1,​2,​3,​4,​5,​6-​η)​-​1-​methyl-​4-​(1-​methylethyl)​benzene]​-​, hexafluorophosphate(​1-​) (1:1)

SMILES Code: CC1=CC=C(C(C)C)C=C1>>CN(C)C2=CC=C([N]3=NC4=CC=CC=[N]4[Os+]3I)C=C2.F[P-](F)(F)(F)(F)F

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1. Fu Y.; Habtemariam A.; Pizarro A. M.; van Rijt S. H.; Healey D. J.; Cooper P.; Shnyder S. D.; Clarkson G. J.; Sadler P. J. Organometallic Osmium Arene Complexes with Potent Cancer Cell Cytotoxicity. J. Med. Chem. 2010, 53, 8192–8196.10.1021/jm100560f

2. Romero-Canelón I, Mos M, Sadler PJ. Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation. J Med Chem. 2015 Oct 8;58(19):7874-80. doi: 10.1021/acs.jmedchem.5b00655. Epub 2015 Sep 23. PubMed PMID: 26397305; PubMed Central PMCID: PMC4601049.