WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 318397

CAS#: 604-75-1

Description: Oxazepam is a short-to-intermediate-acting benzodiazepine. It is used for the treatment of anxiety and insomnia and in the control of symptoms of alcohol withdrawal. Oxazepam is a metabolite of diazepam, prazepam, and temazepam, and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties compared to other benzodiazepines. Oxazepam is discontinued.

Chemical Structure

CAS# 604-75-1

Theoretical Analysis

MedKoo Cat#: 318397
Name: Oxazepam
CAS#: 604-75-1
Chemical Formula: C15H11ClN2O2
Exact Mass: 286.0509
Molecular Weight: 286.713
Elemental Analysis: C, 62.84; H, 3.87; Cl, 12.37; N, 9.77; O, 11.16

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Oxazepam, Adumbran, Serax, Tazepam

IUPAC/Chemical Name: 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one


InChi Code: InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 286.713 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Goeders NE, Guerin GF, Schmoutz CD. The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions. Adv Pharmacol. 2014;69:419-79. doi: 10.1016/B978-0-12-420118-7.00011-1. Review. PubMed PMID: 24484984.

2: Larsen J, Arnberg A, Brøsen K. [Tramadol and oxazepam. Effect on pulmonry function in elderly patients with chronic obstructive lung disease]. Ugeskr Laeger. 2001 Jan 22;163(4):458-60. Review. Danish. PubMed PMID: 11218788.

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5: Greenblatt DJ. Clinical pharmacokinetics of oxazepam and lorazepam. Clin Pharmacokinet. 1981 Mar-Apr;6(2):89-105. Review. PubMed PMID: 6111408.

6: Garattini S. Biochemical and pharmacological properties of oxazepam. Acta Psychiatr Scand Suppl. 1978;(274):9-18. Review. PubMed PMID: 367059.

7: Oxazepam. IARC Monogr Eval Carcinog Risks Hum. 1996;66:115-42. Review. PubMed PMID: 9097121.

8: Ayd FJ Jr. Oxazepam: update 1989. Int Clin Psychopharmacol. 1990 Jan;5(1):1-15. Review. PubMed PMID: 2185302.

9: Kitani K, Klotz U, Kanai S, Sato Y, Ohta M, Nokubo M. Age-related differences in the coordination disturbance and anticonvulsant effect of oxazepam in mice. Arch Gerontol Geriatr. 1989 Jul;9(1):31-43. Review. PubMed PMID: 2675790.

10: Lader MH. The clinical pharmacology of oxazepam. Acta Psychiatr Scand Suppl. 1978;(274):89-93. Review. PubMed PMID: 367058.

11: Greenblatt DJ, Shader RI, Koch-Weser J. Pharmacokinetics in clinical medicine: oxazepam versus other benzodiazepines. Dis Nerv Syst. 1975 May;36(5 Pt. 2):6-13. Review. PubMed PMID: 1095326.

12: Blackwell B. A critical review of oxazepam: efficacy and specificity. Dis Nerv Syst. 1975 May;36(5 Pt. 2):17-22. Review. PubMed PMID: 1095324.