Orders received during 11/25~11/29 will be shipped in 11/30/2020 due to Thanksgiving holiday.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 318371

CAS#: 39562-70-4

Description: Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 180 2 Weeks
10mg USD 250 2 Weeks
25mg USD 350 2 Weeks
50mg USD 450 2 Weeks
100mg USD 550 2 Weeks
200mg USD 650 2 Weeks
500mg USD 850 2 Weeks
1g USD 1050 2 Weeks
2g USD 1450 2 Weeks
5g USD 1650 2 Weeks
10g USD 1950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-11-25. Prices are subject to change without notice.

Nitrendipine, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 318371
Name: Nitrendipine
CAS#: 39562-70-4
Chemical Formula: C18H20N2O6
Exact Mass: 360.1321
Molecular Weight: 360.3612
Elemental Analysis: C, 59.99; H, 5.59; N, 7.77; O, 26.64

Synonym: Nitrendipine, Bayotensin, Baypress, Nidrel, Deiten

IUPAC/Chemical Name: 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate


InChi Code: InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3

SMILES Code: CCOC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC([N+]([O-])=O)=CC=C2)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Siddiqui MA, Plosker GL. Fixed-dose combination enalapril/nitrendipine: a review of its use in mild-to-moderate hypertension. Drugs. 2004;64(10):1135-48. Review. PubMed PMID: 15139792.

2: Mancini M, Marotta T, Ferrara LA. Metabolic neutrality in nitrendipine therapy. J Cardiovasc Pharmacol. 1991;18 Suppl 1:S30-3. Review. PubMed PMID: 1723452.

3: Santiago TM, Lopez LM. Nitrendipine: a new dihydropyridine calcium-channel antagonist for the treatment of hypertension. DICP. 1990 Feb;24(2):167-75. Review. PubMed PMID: 2408259.

4: Hasegawa GR. Nicardipine, nitrendipine, and bepridil: new calcium antagonists for cardiovascular disorders. Clin Pharm. 1988 Feb;7(2):97-108. Review. PubMed PMID: 3280222.

5: Vanov SK, Pun EF, Taylor RJ. The safety of nitrendipine in the treatment of essential hypertension--a review of 61 clinical studies. Angiology. 1988 Jan;39(1 Pt 2):113-22. Review. PubMed PMID: 3277492.

6: Zanchetti A. Nitrendipine and ACE inhibitors. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S80-5. Review. PubMed PMID: 2468881.

7: Hanbauer I, Sanna E. Presence in brain of an endogenous ligand for nitrendipine-binding sites that modulates Ca2+ channel activity. Ann N Y Acad Sci. 1988;522:96-105. Review. PubMed PMID: 2454061.

8: Ferrara LA, Marotta T. Nitrendipine and metabolic balance. J Cardiovasc Pharmacol. 1991;18 Suppl 5:S19-21. Review. PubMed PMID: 1725797.

9: Ruilope LM. Renal effects of nitrendipine. J Cardiovasc Pharmacol. 1991;18 Suppl 5:S10-3. Review. PubMed PMID: 1725795.

10: Byyny RL. Epidemiologic aspects of elderly hypertensive patients and the results of treatment with nitrendipine. J Cardiovasc Pharmacol. 1989;14 Suppl 10:S27-32; discussion S59-62. Review. PubMed PMID: 2483568.

11: Mac Carthy EP. Combination therapy of hypertension with beta-adrenoceptor blockers and the calcium channel antagonist nitrendipine. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S76-9. Review. PubMed PMID: 2468880.

12: Eichelbaum M, Mikus G, Mast V, Fischer C, Kuhlmann U, Machleidt C. Pharmacokinetics and pharmacodynamics of nitrendipine in healthy subjects and patients with kidney and liver disease. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S6-10. Review. PubMed PMID: 2468876.

13: Hulthén UL, Katzman PL. Review of long-term trials with nitrendipine. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S11-5. Review. PubMed PMID: 2468850.

14: Kazda S, Hirth C, Stasch JP. Diuretic effect of nitrendipine contributes to its antihypertensive efficacy: a review. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S1-5. Review. PubMed PMID: 2468846.

15: Goa KL, Sorkin EM. Nitrendipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of hypertension. Drugs. 1987 Feb;33(2):123-55. Review. PubMed PMID: 3552592.

16: Trost BN, Weidmann P. Effects of nitrendipine and other calcium antagonists on glucose metabolism in man. J Cardiovasc Pharmacol. 1984;6 Suppl 7:S986-95. Review. PubMed PMID: 6085390.