IDO-IN-1
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406739

CAS#: 914638-30-5

Description: IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM. IDO-IN-1 showed in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.


Chemical Structure

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IDO-IN-1
CAS# 914638-30-5

Theoretical Analysis

MedKoo Cat#: 406739
Name: IDO-IN-1
CAS#: 914638-30-5
Chemical Formula: C9H7BrFN5O2
Exact Mass: 314.98
Molecular Weight: 316.090
Elemental Analysis: C, 34.20; H, 2.23; Br, 25.28; F, 6.01; N, 22.16; O, 10.12

Price and Availability

Size Price Availability Quantity
100mg USD 950 2 Weeks
200mg USD 1550 2 Weeks
500mg USD 2850 2 Weeks
1g USD 3950 2 Weeks
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Synonym: IDO-IN-1; IDO-IN1; IDO-IN 1.

IUPAC/Chemical Name: (Z)-4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide

InChi Key: ORHZJUSHZUCMKR-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H7BrFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)

SMILES Code: FC1=CC=C(/N=C(C2=NON=C2N)\NO)C=C1Br

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 316.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Yue EW, Douty B, Wayland B, Bower M, Liu X, Leffet L, Wang Q, Bowman KJ,
Hansbury MJ, Liu C, Wei M, Li Y, Wynn R, Burn TC, Koblish HK, Fridman JS, Metcalf
B, Scherle PA, Combs AP. Discovery of potent competitive inhibitors of
indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in
a mouse melanoma model. J Med Chem. 2009 Dec 10;52(23):7364-7. doi:
10.1021/jm900518f. PubMed PMID: 19507862.