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IDO-IN-1
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406739

CAS#: 914638-30-5

Description: IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50 of 59 nM. IDO-IN-1 showed in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.


Price and Availability

Size Price Shipping out time Quantity
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 950 2 Weeks
500mg USD 1450 2 Weeks
1g USD 2450 2 Weeks
2g USD 3950 2 Weeks
Inquire bulk and customized quantity
Pricing updated 2020-10-23. Prices are subject to change without notice.

IDO-IN-1, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 406739
Name: IDO-IN-1
CAS#: 914638-30-5
Chemical Formula: C9H7BrFN5O2
Exact Mass: 314.9767
Molecular Weight: 316.0904
Elemental Analysis: C, 34.20; H, 2.23; Br, 25.28; F, 6.01; N, 22.16; O, 10.12


Synonym: IDO-IN-1; IDO-IN1; IDO-IN 1.

IUPAC/Chemical Name: (Z)-4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide

InChi Key: ORHZJUSHZUCMKR-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H7BrFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)

SMILES Code: FC1=CC=C(/N=C(C2=NON=C2N)\NO)C=C1Br


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Yue EW, Douty B, Wayland B, Bower M, Liu X, Leffet L, Wang Q, Bowman KJ,
Hansbury MJ, Liu C, Wei M, Li Y, Wynn R, Burn TC, Koblish HK, Fridman JS, Metcalf
B, Scherle PA, Combs AP. Discovery of potent competitive inhibitors of
indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in
a mouse melanoma model. J Med Chem. 2009 Dec 10;52(23):7364-7. doi:
10.1021/jm900518f. PubMed PMID: 19507862.