AZD-5423
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524346

CAS#: 1034148-04-3

Description: AZD5423 is a nonsteroidal glucocorticoid by AstraZeneca used to treat respiratory diseases and in particular chronic obstructive pulmonary disease.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 1250 2 Weeks
200mg USD 1950 2 Weeks
500mg USD 2850 2 Weeks
1g USD 3650 2 Weeks
2g USD 5450 2 Weeks
5g USD 7950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-20. Prices are subject to change without notice.

AZD-5423, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 524346
Name: AZD-5423
CAS#: 1034148-04-3
Chemical Formula: C25H21F4N3O3
Exact Mass: 487.1519
Molecular Weight: 487.45
Elemental Analysis: C, 61.60; H, 4.34; F, 15.59; N, 8.62; O, 9.85


Synonym: AZD-5423; AZD 5423; AZD5423; UNII-641H0Q518W;

IUPAC/Chemical Name: 2,2,2-Trifluoro-N-((1R,2S)-1-((1-(4-fluorophenyl)-1H-indazol-5-yl)oxy)-1-(3-methoxyphenyl)-2-propanyl)acetamide

InChi Key: FCNQMDSJHADDFT-WNSKOXEYSA-N

InChi Code: InChI=1S/C25H21F4N3O3/c1-15(31-24(33)25(27,28)29)23(16-4-3-5-20(12-16)34-2)35-21-10-11-22-17(13-21)14-30-32(22)19-8-6-18(26)7-9-19/h3-15,23H,1-2H3,(H,31,33)/t15-,23-/m0/s1

SMILES Code: C[C@@H]([C@@H](c1cccc(c1)OC)Oc2ccc3c(c2)cnn3c4ccc(cc4)F)NC(=O)C(F)(F)F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Norman P. Crystalline forms of 2,2,2-trifluoro-N-[(1R,2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-metho xyphenyl)-2-propanyl]acetamide (AZD-5423). Expert Opin Ther Pat. 2013 Sep;23(9):1239-45. doi: 10.1517/13543776.2013.820706. Epub 2013 Jul 19. PubMed PMID: 23865465.