Amedalin Hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524204

CAS#: 22232-73-1

Description: Amadalin Hydrochloride is an antidepressant. Amadalin Hydrochloride is a bio-active chemical. Detailed information has not been published.


Chemical Structure

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Amedalin Hydrochloride
CAS# 22232-73-1

Theoretical Analysis

MedKoo Cat#: 524204
Name: Amedalin Hydrochloride
CAS#: 22232-73-1
Chemical Formula: C19H23ClN2O
Exact Mass: 0.00
Molecular Weight: 330.850
Elemental Analysis: C, 68.97; H, 7.01; Cl, 10.72; N, 8.47; O, 4.84

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Amedalin Hydrochloride; Amedalin Hydrochloride [USAN]; Amedalin HCl; UNII-0EMF539HN0; UK 3540-1;

IUPAC/Chemical Name: 2H-Indol-2-one, 1,3-dihydro-3-methyl-3-(3-(methylamino)propyl)-1-phenyl-, monohydrochloride

InChi Key: DDOCDXCKSVDRHL-FYZYNONXSA-N

InChi Code: InChI=1S/C19H22N2O.ClH/c1-19(13-8-14-20-2)16-11-6-7-12-17(16)21(18(19)22)15-9-4-3-5-10-15;/h3-7,9-12,20H,8,13-14H2,1-2H3;1H/t19-;/m0./s1

SMILES Code: N1(c2c(cccc2)[C@@](C1=O)(CCCNC)C)c1ccccc1.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 330.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Song S, Chen F, Xing X, Ren M, Ma Q, Xie Y, Tang Q, Luo J. Concurrent quantification and comparative pharmacokinetic analysis of bioactive compounds in the Herba Ephedrae-Semen Armeniacae Amarum herb pair. J Pharm Biomed Anal. 2015 May 10;109:67-73. doi: 10.1016/j.jpba.2015.02.004. Epub 2015 Feb 14. PubMed PMID: 25766850.

2: Zheng M, Zhou H, Wan H, Chen YL, He Y. Effects of herbal drugs in Mahuang decoction and their main components on intestinal transport characteristics of Ephedra alkaloids evaluated by a Caco-2 cell monolayer model. J Ethnopharmacol. 2015 Apr 22;164:22-9. doi: 10.1016/j.jep.2015.01.043. Epub 2015 Feb 7. PubMed PMID: 25660335.

3: Yang DB, Tong Y, Ma ZS, Wang L, Dong MH, Li YL, Wang JY. [Simultaneous determination of ephedrine hydrochloride, D-pseudoephedrine and amygdalin in xiao'er pingchuan qutan granule by HPLC]. Zhongguo Zhong Yao Za Zhi. 2013 Mar;38(5):687-90. Chinese. PubMed PMID: 23724676.

4: Liu L, Duan JA, Tang Y, Guo J, Yang N, Ma H, Shi X. Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. J Ethnopharmacol. 2012 Jan 31;139(2):381-7. doi: 10.1016/j.jep.2011.11.016. Epub 2011 Nov 20. PubMed PMID: 22123200.

5: Cancilla DA, Que Hee SS. O-(2,3,4,5,6-pentafluorophenyl)methylhydroxylamine hydrochloride: a versatile reagent for the determination of carbonyl-containing compounds. J Chromatogr. 1992 Dec 25;627(1-2):1-16. Review. PubMed PMID: 1487522.

6: Nevada. Prescribing, administering amygdalin or procaine hydrochloride as grounds for disciplinary action. Nev Revis Statut Nev. 1977;Section 633.521 1977:Unknown. PubMed PMID: 12041369.

7: Nevada. Prescribing, administering amygdalin or procaine hydrochloride as grounds for disciplinary action. Nev Revis Statut Nev. 1977;Section 630.303 1977:Unknown. PubMed PMID: 12041368.