ABT 491 Hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524107

CAS#: 189689-94-9

Description: ABT-491 hydrochloride is a highly potent, selective and orally active platelet-activating factor receptor (PAF-R) antagonist.

Price and Availability




ABT 491, purity > 98%, is not in stock, may be available through custom synthesis. Minimum 1 gram order is requested. Current shipping out time is about 70 days after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 524107
Name: ABT 491 Hydrochloride
CAS#: 189689-94-9
Chemical Formula: C28H23ClFN5O2
Exact Mass:
Molecular Weight: 515.97
Elemental Analysis: C, 65.18; H, 4.49; Cl, 6.87; F, 3.68; N, 13.57; O, 6.20

Synonym: ABT 491 hydrochloride; ABT 491; ABT-491; ABT491;

IUPAC/Chemical Name: 1H-Indole-1-carboxamide, 4-ethynyl-3-(3-fluoro-4-((2-methyl-1H-imidazo(4,5-c)pyridin-1-yl)methyl)benzoyl)-N,N-dimethyl-, monohydrochloride


InChi Code: InChI=1S/C28H22FN5O2.ClH/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33;/h1,6-14,16H,15H2,2-4H3;1H

SMILES Code: O=C(N1C=C(C(C2=CC=C(CN3C(C)=NC4=C3C=CN=C4)C(F)=C2)=O)C5=C1C=CC=C5C#C)N(C)C.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


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