WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524103

CAS#: 129639-79-8

Description: Abafungin is a broad-spectrum antifungal agent.

Chemical Structure

CAS# 129639-79-8

Theoretical Analysis

MedKoo Cat#: 524103
Name: Abafungin
CAS#: 129639-79-8
Chemical Formula: C21H22N4OS
Exact Mass: 378.15143
Molecular Weight: 378.49
Elemental Analysis: C, 66.64; H, 5.86; N, 14.80; O, 4.23; S, 8.47

Price and Availability

Size Price Availability Quantity
50.0mg USD 330.0 2 Weeks
100.0mg USD 550.0 2 Weeks
250.0mg USD 950.0 2 Weeks
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Synonym: Abafungin; Bay w 6341; UNII-11DI31LWXF;

IUPAC/Chemical Name: Hexahydro-2-((4-(o-(2,4-xylyloxy)phenyl)-2-thiazolyl)imino)pyrimidine


InChi Code: InChI=1S/C21H22N4OS/c1-14-8-9-18(15(2)12-14)26-19-7-4-3-6-16(19)17-13-27-21(24-17)25-20-22-10-5-11-23-20/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H2,22,23,24,25)


Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certificate of Analysis:

Safety Data Sheet (SDS):

Preparing Stock Solutions

The following data is based on the product molecular weight 378.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Rouf A, Tanyeli C. Bioactive thiazole and benzothiazole derivatives. Eur J Med Chem. 2015 Jun 5;97:911-27. doi: 10.1016/j.ejmech.2014.10.058. Epub 2014 Oct 22. PMID: 25455640.

2: Borelli C, Schaller M, Niewerth M, Nocker K, Baasner B, Berg D, Tiemann R, Tietjen K, Fugmann B, Lang-Fugmann S, Korting HC. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-59. doi: 10.1159/000142334. Epub 2008 Jun 30. PMID: 18587237; PMCID: PMC2818358.

3: Kumawat MK. Thiazole Containing Heterocycles with Antimalarial Activity. Curr Drug Discov Technol. 2018;15(3):196-200. doi: 10.2174/1570163814666170725114159. PMID: 28745209.

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5: Chhabria MT, Patel S, Modi P, Brahmkshatriya PS. Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives. Curr Top Med Chem. 2016;16(26):2841-2862. doi: 10.2174/1568026616666160506130731. PMID: 27150376.

6: Mabkhot YN, Alharbi MM, Al-Showiman SS, Ghabbour HA, Kheder NA, Soliman SM, Frey W. Stereoselective synthesis, X-ray analysis, computational studies and biological evaluation of new thiazole derivatives as potential anticancer agents. Chem Cent J. 2018 May 11;12(1):56. doi: 10.1186/s13065-018-0420-7. PMID: 29748782; PMCID: PMC5945573.