WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407421

CAS#: 74588-78-6

Description: D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell proliferation in vitro (IC50 = 74 nM). In xenograft experiments with the human amelanoic melanoma MEXF 989, D-64131 was highly active with treatment resulting in a growth delay of 23.4 days at 400 mg/kg.

Price and Availability

Size Price Shipping out time Quantity
25mg USD 190 2 Weeks
50mg USD 350 2 Weeks
100mg USD 550 2 Weeks
200mg USD 850 2 Weeks
500mg USD 1650 2 Weeks
1g USD 2450 2 Weeks
2g USD 4250 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

D-64131, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407421
Name: D-64131
CAS#: 74588-78-6
Chemical Formula: C16H13NO2
Exact Mass: 251.0946
Molecular Weight: 251.285
Elemental Analysis: C, 76.48; H, 5.21; N, 5.57; O, 12.73

Synonym: D-64131; D 64131; D64131.

IUPAC/Chemical Name: (5-Methoxy-1H-indol-2-yl)phenylmeth​anone


InChi Code: InChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3

SMILES Code: O=C(C(N1)=CC2=C1C=CC(OC)=C2)C3=CC=CC=C3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Putey A, Popowycz F, Do QT, Bernard P, Talapatra SK, Kozielski F, Galmarini
CM, Joseph B. Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives
as tubulin polymerization inhibitors: synthesis and structure--activity
relationship studies. J Med Chem. 2009 Oct 8;52(19):5916-25. doi:
10.1021/jm900476c. PubMed PMID: 19743863.

2: Beckers T, Reissmann T, Schmidt M, Burger AM, Fiebig HH, Vanhoefer U, Pongratz
H, Hufsky H, Hockemeyer J, Frieser M, Mahboobi S. 2-aroylindoles, a novel class
of potent, orally active small molecule tubulin inhibitors. Cancer Res. 2002 Jun
1;62(11):3113-9. PubMed PMID: 12036922.