WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 522715

CAS#: 348575-88-2

Description: Optovin is a photoactive TRPA1 activator. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues. In animals with severed spinal cords, optovin treatment enables control of motor activity in the paralyzed extremities by localized illumination. These studies identify a light-based strategy for controlling endogenous TRPA1 receptors in vivo, with potential clinical and research applications in nontransgenic animals, including humans.

Chemical Structure

CAS# 348575-88-2

Theoretical Analysis

MedKoo Cat#: 522715
Name: Optovin
CAS#: 348575-88-2
Chemical Formula: C15H13N3OS2
Exact Mass: 315.05
Molecular Weight: 315.409
Elemental Analysis: C, 57.12; H, 4.15; N, 13.32; O, 5.07; S, 20.33

Price and Availability

Size Price Availability Quantity
100.0mg USD 450.0 2 Weeks
200.0mg USD 750.0 2 Weeks
500.0mg USD 1450.0 2 Weeks
1.0g USD 2250.0 2 Weeks
2.0g USD 3850.0 2 Weeks
5.0g USD 6450.0 2 Weeks
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Synonym: Optovin

IUPAC/Chemical Name: (Z)-5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one


InChi Code: InChI=1S/C15H13N3OS2/c1-9-6-11(7-13-14(19)17-15(20)21-13)10(2)18(9)12-4-3-5-16-8-12/h3-8H,1-2H3,(H,17,19,20)/b13-7-

SMILES Code: O=C1NC(S/C1=C\C2=C(C)N(C3=CC=CN=C3)C(C)=C2)=S

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 315.409 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J,
Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan
DJ, Peterson RT. Photochemical activation of TRPA1 channels in neurons and
animals. Nat Chem Biol. 2013 Apr;9(4):257-63. doi: 10.1038/nchembio.1183. Epub
2013 Feb 10. PubMed PMID: 23396078; PubMed Central PMCID: PMC3604056.


100.0mg / USD 450.0