WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 318682
CAS#: 18559-94-9 (free base)
Description: Salbutamol is a β2-AR agonist. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart.
MedKoo Cat#: 318682
Name: Salbutamol
CAS#: 18559-94-9 (free base)
Chemical Formula: C13H21NO3
Exact Mass: 239.15214
Molecular Weight: 239.31
Elemental Analysis: C, 65.25; H, 8.84; N, 5.85; O, 20.06
Related CAS #: 51022-70-9 (sulfate) 18559-94-9 (free base) 51293-66-4 (HCl)
Synonym: Salbutamol; Albuterol; Proventil; Sultanol; Aerolin; Albuterol Sulfate; Proventil; Salbutamol; Sultanol; Ventolin;
IUPAC/Chemical Name: 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
InChi Key: NDAUXUAQIAJITI-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
SMILES Code: CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 239.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Chen D, Yang M, Zheng N, Xie N, Liu D, Xie C, Yao D. A novel aptasensor for
electrochemical detection of ractopamine, clenbuterol, salbutamol,
phenylethanolamine and procaterol. Biosens Bioelectron. 2016 Jun 15;80:525-31.
doi: 10.1016/j.bios.2016.01.025. Epub 2016 Jan 11. PubMed PMID: 26890828.
2: Wang MY, Zhu W, Ma L, Ma JJ, Zhang DE, Tong ZW, Chen J. Enhanced simultaneous detection of ractopamine and salbutamol--Via electrochemical-facial deposition of MnO2 nanoflowers onto 3D RGO/Ni foam templates. Biosens Bioelectron. 2016 Apr15;78:259-66. doi: 10.1016/j.bios.2015.11.062. Epub 2015 Nov 22. PubMed PMID:26623510.
3: Flores P, Mendes AL, Neto AS. A randomized trial of nebulized 3% hypertonic
saline with salbutamol in the treatment of acute bronchiolitis in hospitalized
infants. Pediatr Pulmonol. 2016 Apr;51(4):418-25. doi: 10.1002/ppul.23306. Epub
2015 Sep 3. PubMed PMID: 26334188.
4: Rodríguez-Ramos F, Andrade-Moreno MÁ, Alfaro-Romero A, Balderas-López JL,
Navarrete A. Gnaphaliin A and gnaphaliin B synergize the relaxant effect of
salbutamol but not of ipratropium in guinea pig trachea. J Pharm Pharmacol. 2016
Apr 7. doi: 10.1111/jphp.12536. [Epub ahead of print] PubMed PMID: 27061296.
5: Andrzejowski P, Carroll W. Salbutamol in paediatrics: pharmacology,
prescribing and controversies. Arch Dis Child Educ Pract Ed. 2016 Apr 8. pii:
edpract-2014-307285. doi: 10.1136/archdischild-2014-307285. [Epub ahead of print] PubMed PMID: 27059284.
