WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407325

CAS#: 18550-98-6

Description: 3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be useful agents in combination with other drugs that inhibit cancer cell proliferation. PFKFB3 inhibitors suppress glucose uptake, which in turn causes an increase in autophagy. The addition of selective inhibitors of autophagy to 3PO and its more potent derivatives may prove useful as rational combinations for the treatment of cancer. Note: this product has been assigned 2 CAS#: 18550-98-6 and 13309-08-5,

Price and Availability

Size Price Shipping out time Quantity
100mg USD 150 Same day
200mg USD 250 Same day
500mg USD 550 Same day
1g USD 850 Same day
2g USD 1250 Same day
5g USD 1950 Same day
Inquire bulk and customized quantity

Pricing updated 2021-01-24. Prices are subject to change without notice.

3PO, purity > 98%, is in stock. The same day shipping after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407325
Name: 3PO
CAS#: 18550-98-6
Chemical Formula: C13H10N2O
Exact Mass: 210.0793
Molecular Weight: 210.236
Elemental Analysis: C, 74.27; H, 4.79; N, 13.33; O, 7.61

Related CAS #: 18550-98-6   13309-08-5    

Synonym: 3PO

IUPAC/Chemical Name: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one


InChi Code: InChI=1S/C13H10N2O/c16-13(12-5-8-14-9-6-12)4-3-11-2-1-7-15-10-11/h1-10H/b4-3+


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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5: Lea MA, Altayyar M, desBordes C. Inhibition of Growth of Bladder Cancer Cells by 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one in Combination with Other Compounds Affecting Glucose Metabolism. Anticancer Res. 2015 Nov;35(11):5889-99. PubMed PMID: 26504012.

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(Last updated: 4/20/2016).