Dimethylenastron
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407308

CAS#: 863774-58-7

Description: Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours.


Price and Availability

Size Price Shipping out time Quantity
25mg USD 250 2 weeks
50mg USD 450 2 weeks
100mg USD 650 2 weeks
200mg USD 950 2 weeks
500mg USD 1950 2 weeks
1g USD 2950 2 weeks
2g USD 3950 2 weeks
5g USD 5850 2 weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-28. Prices are subject to change without notice.

Dimethylenastron, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 407308
Name: Dimethylenastron
CAS#: 863774-58-7
Chemical Formula: C16H18N2O2S
Exact Mass: 302.1089
Molecular Weight: 302.392
Elemental Analysis: C, 63.55; H, 6.00; N, 9.26; O, 10.58; S, 10.60


Synonym: Dimethylenastron.

IUPAC/Chemical Name: 2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone

InChi Key: RUOOPLOUUAYNPY-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)

SMILES Code: O=C1C2=C(NC(NC2C3=CC=CC(O)=C3)=S)CC(C)(C)C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001