NVP CXCR2 20

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 523109

CAS#: 1029521-30-9

Description: NVP CXCR2 20 is a potent and selective CXCR2 antagonist (IC50 = 40 nM). It exhibits selectivity for CXCR2 over a panel of 49 other GPCRs and is orally bioavailable.


Price and Availability

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NVP CXCR2 20 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 523109
Name: NVP CXCR2 20
CAS#: 1029521-30-9
Chemical Formula: C15H11F2N3OS
Exact Mass: 319.05909
Molecular Weight: 319.33
Elemental Analysis: C, 56.42; H, 3.47; F, 11.90; N, 13.16; O, 5.01; S, 10.04


Synonym: NVP-CXCR2 20; NVP CXCR2-20; NVP CXCR220.

IUPAC/Chemical Name: 4-Cyclopropyl-2-[[(2,3-difluorophenyl)methyl]thio]-1,6-dihydro-6-oxo5-pyrimidinecarbonitrile

InChi Key: PHHZYKZFEBRXAL-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H11F2N3OS/c16-11-3-1-2-9(12(11)17)7-22-15-19-13(8-4-5-8)10(6-18)14(21)20-15/h1-3,8H,4-5,7H2,(H,19,20,21)

SMILES Code: N#CC1=C(C2CC2)N=C(SCC3=CC=CC(F)=C3F)NC1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490