WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407299

CAS#: 325970-71-6

Description: L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC₅₀ values of 10 μM and 10 μM.). L67 significantly increased the cytotoxicity of DNA-damaging.

Price and Availability

Size Price Shipping out time Quantity
50mg USD 150 Same day
100mg USD 250 Same day
200mg USD 450 Same day
500mg USD 850 Same day
1g USD 1450 Same day
2g USD 2450 Same day
Inquire bulk and customized quantity

Pricing updated 2021-01-27. Prices are subject to change without notice.

L67, purity > 98%, is in stock. The same day shipping out after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407299
Name: L67
CAS#: 325970-71-6
Chemical Formula: C16H14Br2N4O4
Exact Mass: 483.9382
Molecular Weight: 486.12
Elemental Analysis: C, 39.53; H, 2.90; Br, 32.87; N, 11.53; O, 13.16

Synonym: L67; L-67; L 67.

IUPAC/Chemical Name: E-2-((3,5-Dibromo-4-methylphenyl)amino)-N’-(2-hydroxy-5-nitrobenzylidene)acetohydrazide


InChi Code: InChI=1S/C16H14Br2N4O4/c1-9-13(17)5-11(6-14(9)18)19-8-16(24)21-20-7-10-4-12(22(25)26)2-3-15(10)23/h2-7,19,23H,8H2,1H3,(H,21,24)/b20-7+

SMILES Code: O=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)CNC2=CC(Br)=C(C)C(Br)=C2

Technical Data

Light yellow to yellow solid powder.

>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell
AD Jr, Tomkinson AE. Rational design of human DNA ligase inhibitors that target
cellular DNA replication and repair. Cancer Res. 2008 May 1;68(9):3169-77. doi:
10.1158/0008-5472.CAN-07-6636. PubMed PMID: 18451142; PubMed Central PMCID: