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TUG-770
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 522663

CAS#: 1402601-82-4

Description: TUG-770 is a Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and currently attracts high interest as a new target for the treatment of type 2 diabetes.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 1250 2 Weeks
200mg USD 1750 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3250 2 Weeks
2g USD 4950 2 Weeks
5g USD 9450 2 Weeks
Inquire bulk and customized quantity
Pricing updated 2020-10-27. Prices are subject to change without notice.

TUG-770, purity > 98%, is in stock. Minimum order is 100mg. Current shipping out time is about 2 weeks after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 522663
Name: TUG-770
CAS#: 1402601-82-4
Chemical Formula: C19H14FNO2
Exact Mass: 307.1009
Molecular Weight: 307.3244
Elemental Analysis: C, 74.26; H, 4.59; F, 6.18; N, 4.56; O, 10.41


Synonym: TUG-770; TUG 770; TUG770.

IUPAC/Chemical Name: 3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid

InChi Key: KIZUBVPJNPVIIN-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)

SMILES Code: O=C(O)CCC1=CC=C(C#CC2=CC=CC=C2CC#N)C=C1F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Christiansen E, Hansen SV, Urban C, Hudson BD, Wargent ET, Grundmann M,
Jenkins L, Zaibi M, Stocker CJ, Ullrich S, Kostenis E, Kassack MU, Milligan G,
Cawthorne MA, Ulven T. Discovery of TUG-770: A Highly Potent Free Fatty Acid
Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes. ACS Med Chem
Lett. 2013 May 9;4(5):441-445. Epub 2013 Apr 8. PubMed PMID: 23687558; PubMed
Central PMCID: PMC3654565.