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MedKoo CAT#: 407293

CAS#: 1316652-41-1

Description: NCC-149 is a HDAC8 inhibitor.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 390 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-03. Prices are subject to change without notice.

NCC-149, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 407293
Name: NCC-149
CAS#: 1316652-41-1
Chemical Formula: C16H14N4O2S
Exact Mass: 326.0837
Molecular Weight: 326.374
Elemental Analysis: C, 58.88; H, 4.32; N, 17.17; O, 9.80; S, 9.82

Synonym: NCC-149; NCC 149; NCC149.

IUPAC/Chemical Name: N-hydroxy-3-(1-((phenylthio)methyl)-1H-1,2,3-triazol-4-yl)benzamide


InChi Code: InChI=1S/C16H14N4O2S/c21-16(18-22)13-6-4-5-12(9-13)15-10-20(19-17-15)11-23-14-7-2-1-3-8-14/h1-10,22H,11H2,(H,18,21)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1. Identification of a Novel Aminotetralin Class of HDAC6 and HDAC8 Selective Inhibitors. By Tang, Guozhi; Wong, Jason C.; Zhang, Weixing; Wang, Zhanguo; Zhang, Nan; Peng, Zhenghong; Zhang, Zhenshan; Rong, Yiping; Li, Shijie; Zhang, Meifang; et al. From Journal of Medicinal Chemistry (2014), 57(19), 8026-8034.

2. Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-​Selective Inhibitors. By Suzuki, Takayoshi; Muto, Nobusuke; Bando, Masashige; Itoh, Yukihiro; Masaki, Ayako; Ri, Masaki; Ota, Yosuke; Nakagawa, Hidehiko; Iida, Shinsuke; Shirahige, Katsuhiko; et al. From ChemMedChem (2014), 9(3), 657-664.

3. Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries. Suzuki, Takayoshi; Ota, Yosuke; Ri, Masaki; Bando, Masashige; Gotoh, Aogu; Itoh, Yukihiro; Tsumoto, Hiroki; Tatum, Prima R.; Mizukami, Tamio; Nakagawa, Hidehiko; et al. From Journal of Medicinal Chemistry (2012), 55(22), 9562-9575.

4. Preparation of hydroxamic acid derivatives as HDAC8 inhibitors. By Miyata, Naoki; Suzuki, Takayoshi; Ota, Yosuke; Ueda, Ryuzo; Iida, Shinsuke; Ri, Masaki. From PCT Int. Appl. (2011), WO 2011089995 A1 20110728.