WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317988

CAS#: 777-11-7

Description: Haloprogin is an antifungal agent used as a topical cream to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik. It was marketed over the counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.

Price and Availability


USD 250
USD 550
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USD 350
USD 650
USD 1450
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USD 450
USD 850
USD 1550

Haloprogin, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 317988
Name: Haloprogin
CAS#: 777-11-7
Chemical Formula: C9H4Cl3IO
Exact Mass: 359.83724
Molecular Weight: 361.39
Elemental Analysis: C, 29.91; H, 1.12; Cl, 29.43; I, 35.12; O, 4.43

Synonym: Haloprogin; Mycanden; Halotex; Mycilan; Polik; Haloproginum; Théraplix Brand of Haloprogin; Westwood Squibb brand of haloprogin;

IUPAC/Chemical Name: 1,2,4-trichloro-5-(3-iodoprop-2-ynoxy)benzene


InChi Code: InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2

SMILES Code: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC#CI

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1: Qadripur SA. [Antimycotic therapy. 2. Antimycotic chemotherapeutic agents:
imidazole derivatives, tolciclate, haloprogin, ciclopiroxolamin]. Fortschr Med.
1983 Mar 10;101(9):355-63. German. PubMed PMID: 6303928.

2: Langsadl L, Jedlickova Z. Sensitivity of strains of Candida albicans to
jaritin, haloprogin, clotrimazole and miconazole. Postgrad Med J. 1979
Sep;55(647):695-6. PubMed PMID: 392487; PubMed Central PMCID: PMC2425642.

3: Clayton YM, Gange RW, Macdonald DM, Carruthers JA. A clinical double-blind
trial of topical haloprogin and miconazole against superficial fungal infections.
Clin Exp Dermatol. 1979 Mar;4(1):65-73. PubMed PMID: 376192.

4: Weitgasser H. [Clinical and myocological study of the antifungal agent
haloprogin]. Mykosen. 1977 Jan;20(1):15-24. German. PubMed PMID: 321954.

5: Rudolph RL. Allergic contact dermatitis caused by haloprogin. Arch Dermatol.
1975 Nov;111(11):1487-8. PubMed PMID: 1242878.

6: de Luca M, Argenziano G. [Haloprogin, a new drug for the local treatment of
dermatomycoses]. Mykosen. 1975 May;18(5):239-44. German. PubMed PMID: 1174260.

7: Hughes WT, Feldman S, Hermann HW. Safety of megadosage haloprogin. Arch
Dermatol. 1974 Dec;110(6):926-8. PubMed PMID: 4479934.

8: Harrison EF, Zygmunt WA. Haloprogin: mode of action studies in Candida
albicans. Can J Microbiol. 1974 Sep;20(9):1241-5. PubMed PMID: 4608935.

9: Haloprogin for tinea. Med Lett Drugs Ther. 1973 Aug 17;15(17):69-70. PubMed
PMID: 4740517.

10: Hermann HW. Clinical efficacy studies of haloprogin, a new topical
antimicrobial agent. Arch Dermatol. 1972 Dec;106(6):839-42. PubMed PMID: 4565229.

11: Hermann HW. Clinical evaluation of haloprogin. Toxicol Appl Pharmacol. 1972
Dec;23(4):598-605. PubMed PMID: 4264777.

12: Carter VH. A controlled study of haloprogin and tolnaftate in tinea pedis.
Curr Ther Res Clin Exp. 1972 Jun;14(6):307-10. PubMed PMID: 4625803.

13: Egere JU, Gugnani HC, Nzelibe FK. Treatment of tropical dermatomycoses with
haloprogin. Mykosen. 1981 Jan;24(1):27-32. PubMed PMID: 6894481.

14: Rudolph RI. Haloprogin as treatment for fungal infections. Clin Exp Dermatol.
1979 Dec;4(4):548. PubMed PMID: 161212.

15: Kessler HJ, Buitrago B, Strauss E. Investigations of the fungicidal activity
of haloprogin. Mykosen. 1978 May;21(5):138-42. PubMed PMID: 580637.

16: Papa CM. Clotrimazole vs haloprogin in the treatment of tinea cruris. Arch
Dermatol. 1978 May;114(5):799-800. PubMed PMID: 580551.

17: Montes LF, Hermann HW. Clinical and antimicrobial effects of haloprogin cream
in diaper dermatitis. Cutis. 1978 Mar;21(3):410-2. PubMed PMID: 580233.

18: Klima J. [Clinical experience with 0.5% jaritin ointment and comparison of
its effectiveness and tolerance with 1% haloprogin ointment (author's transl)].
Cesk Dermatol. 1977 Oct;52(5):319-23. Czech. PubMed PMID: 146569.

19: VanDersarl JV, Sheppard RH. Clotrimazole vs haloprogin treatment of tinea
cruris. Arch Dermatol. 1977 Sep;113(9):1233-5. PubMed PMID: 578400.

20: Berlin AR, Miller OF. Allergic contact dermatitis from ethyl sebacata in
haloprogin cream. Arch Dermatol. 1976 Nov;112(11):1563-4. PubMed PMID: 990052.