WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319771
CAS#: 871351-60-9
Description: Ordopidine, also known as ACR325, is a dopaminergic stabilizer. Ordopidine inhibits psychostimulant-induced hyperactivity, and stimulates behaviour in states of hypoactivity. Ordopidine acts as dopamine D2 receptor antagonists in vitro, albeit with low affinity, their specific state-dependent behavioural effect profile is not shared by D2 receptor antagonists in general.
MedKoo Cat#: 319771
Name: Ordopidine
CAS#: 871351-60-9
Chemical Formula: C14H20FNO2S
Exact Mass: 285.1199
Molecular Weight: 285.3774
Elemental Analysis: C, 58.92; H, 7.06; F, 6.66; N, 4.91; O, 11.21; S, 11.23
Synonym: ACR325; ACR-325; ACR 325; Ordopidine
IUPAC/Chemical Name: 1-Ethyl-4-(2-fluoro-3-(methylsulfonyl)phenyl)piperidine
InChi Key: UKUPJASJNQDHPH-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H20FNO2S/c1-3-16-9-7-11(8-10-16)12-5-4-6-13(14(12)15)19(2,17)18/h4-6,11H,3,7-10H2,1-2H3
SMILES Code: O=S(C1=C(F)C(C2CCN(CC)CC2)=CC=C1)(C)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 285.3774 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Waters S, Ponten H, Edling M, Svanberg B, Klamer D, Waters N. The dopaminergic
stabilizers pridopidine and ordopidine enhance cortico-striatal Arc gene
expression. J Neural Transm (Vienna). 2014 Nov;121(11):1337-47. doi:
10.1007/s00702-014-1231-1. Epub 2014 May 11. PubMed PMID: 24817271.