Lerimazoline

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319658

CAS#: 54765-26-3( free base)

Description: Lerimazoline, also known as Trimazoline, Trimizoline and ST-71, is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus. It causes hypertension.


Chemical Structure

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Lerimazoline
CAS# 54765-26-3( free base)

Theoretical Analysis

MedKoo Cat#: 319658
Name: Lerimazoline
CAS#: 54765-26-3( free base)
Chemical Formula: C13H18N2
Exact Mass: 202.15
Molecular Weight: 202.301
Elemental Analysis: C, 77.18; H, 8.97; N, 13.85

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Related CAS #: 54707-83-4 (HCl)   54765-26-3( free base)  

Synonym: ST-71; ST71; ST 71; Trimazoline; Trimizoline; Lerimazoline.

IUPAC/Chemical Name: 2-(2,4,6-trimethylbenzyl)-4,5-dihydro-1H-imidazole

InChi Key: DUHARNKZLBMPBS-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H18N2/c1-9-6-10(2)12(11(3)7-9)8-13-14-4-5-15-13/h6-7H,4-5,8H2,1-3H3,(H,14,15)

SMILES Code: CC1=C(CC2=NCCN2)C(C)=CC(C)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 202.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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