WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319642
Description: Dagrocorat, also known as PF-00251802, is a glucocorticoid receptor agonist and potential useful for anti-inflammatory diseases.
MedKoo Cat#: 319642
Chemical Formula: C29H29F3N2O2
Exact Mass: 494.2181
Molecular Weight: 494.5582
Elemental Analysis: C, 70.43; H, 5.91; F, 11.52; N, 5.66; O, 6.47
Synonym: PF-00251802; PF 00251802; PF00251802; PF-251802; PF 251802; PF251802; Dagrocorat.
IUPAC/Chemical Name: (4bR,7S,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-2-carboxamide
InChi Key: QJJBNCHSWFGXML-QPVYNBJUSA-N
InChi Code: InChI=1S/C29H29F3N2O2/c1-19-25(8-5-15-33-19)34-26(35)22-10-12-24-21(16-22)9-11-23-18-28(36,29(30,31)32)14-13-27(23,24)17-20-6-3-2-4-7-20/h2-8,10,12,15-16,23,36H,9,11,13-14,17-18H2,1H3,(H,34,35)/t23-,27-,28+/m1/s1
SMILES Code: FC([C@]1(O)CC[C@]2(CC3=CC=CC=C3)C4=CC=C(C(NC5=CC=CN=C5C)=O)C=C4CC[C@]2([H])C1)(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 494.5582 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|