WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 522618
Description: BIA10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest of the body other than the brain and spinal cord). BIA 10-2474 interacts with the human endocannabinoid system. BIA 10-2474 was in development for the treatment of a range of different medical conditions from anxiety to Parkinson's disease, also for the treatment of chronic pain of multiple sclerosis, cancer, hypertension or the treatment of obesity. A clinical trial with this drug was underway in Rennes, France, in which severe adverse events occurred in January 2016 affecting 5 patients, including leading to the death of one.
MedKoo Cat#: 522618
Chemical Formula: C16H20N4O2
Exact Mass: 300.1586
Molecular Weight: 300.362
Elemental Analysis: C, 63.98; H, 6.71; N, 18.65; O, 10.65
Synonym: BIA 10-2474; BIA-10-2474; BIA10-2474.
IUPAC/Chemical Name: 3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide
InChi Key: DOWVMJFBDGWVML-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H20N4O2/c1-18(14-7-3-2-4-8-14)16(21)19-11-15(17-12-19)13-6-5-9-20(22)10-13/h5-6,9-12,14H,2-4,7-8H2,1H3
SMILES Code: O=C(N1C=C(C2=C[N+]([O-])=CC=C2)N=C1)N(C3CCCCC3)C