CYM-50308
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 522588

CAS#: 1345858-76-5

Description: CYM 50308 is a novel agonist of SIP4 (EC50 = 56 nM) that displays 37-fold selectivity against S1P5 (EC50 = 2.1 μM) and no appreciable activity over the S1P1-3 subtypes at concentrations up to 25 μM.

Chemical Structure

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CYM-50308
CAS# 1345858-76-5
Instruction

Theoretical Analysis

MedKoo Cat#: 522588
Name: CYM-50308
CAS#: 1345858-76-5
Chemical Formula: C20H21F2N3O2S
Exact Mass: 405.13
Molecular Weight: 405.464
Elemental Analysis: C, 59.25; H, 5.22; F, 9.37; N, 10.36; O, 7.89; S, 7.91

Price and Availability

Size Price Availability Quantity
10mg USD 190 2 Weeks
25mg USD 350 2 Weeks
50mg USD 550 2 Weeks
100mg USD 950 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 2450 2 Weeks
1g USD 3450 2 Weeks
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Synonym: CYM-50308; CYM 50308; CYM50308.

IUPAC/Chemical Name: (2Z,5Z)-5-((1-(2,4-difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)-2-((2-methoxyethyl)imino)-3-methylthiazolidin-4-one

InChi Key: BKQZKTRCUAWRHT-ZGNGNRKCSA-N

InChi Code: InChI=1S/C20H21F2N3O2S/c1-12-9-14(13(2)25(12)17-6-5-15(21)11-16(17)22)10-18-19(26)24(3)20(28-18)23-7-8-27-4/h5-6,9-11H,7-8H2,1-4H3/b18-10-,23-20-

SMILES Code: FC1=CC(F)=C(C=C1)N2C(C)=CC(/C=C3S/C(N(C\3=O)C)=N\CCOC)=C2C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 405.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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