Echothiophate Iodide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317764

CAS#: 513-10-0

Description: Echothiophate iodide is a potent, long-acting cholinesterase inhibitor used as a miotic in the treatment of glaucoma. Echothiophate iodide covalently binds by its phosphate group to serine group at the active site of the cholinesterase. Once bound, the enzyme is permanently inactive and the cell has to make new enzymes. Echothiophate binds irreversibly to cholinesterase. Because of the very slow rate at which echothiophate is hydrolyzed by cholinesterase, its effects can last a week or more. It is used as an ocular antihypertensive in the treatment of chronic glaucoma and, in some cases, accommodative esotropia. It is available under several trade names such as Phospholine Iodide.

Price and Availability


USD 325

USD 2950

Echothiophate Iodide, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 317764
Name: Echothiophate Iodide
CAS#: 513-10-0
Chemical Formula: C9H23INO3PS
Exact Mass:
Molecular Weight: 383.23
Elemental Analysis: C, 28.21; H, 6.05; I, 33.11; N, 3.65; O, 12.52; P, 8.08; S, 8.37

Synonym: Echothiophate Iodide; Phospholine iodide; Ecothiophate iodide; Echodide; Ecostigmini Sodidum; Iodide, Echothiophate; Iodide, Ecothiopate; Iodide, Ecothiophate; Iodide, Phospholine; Phospholine Iodide;

IUPAC/Chemical Name: 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium;iodide


InChi Code: InChI=1S/C9H23NO3PS.HI/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5;/h6-9H2,1-5H3;1H/q+1;/p-1


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


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Mar 26. PubMed PMID: 25818282.

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