WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317861

CAS#: 104227-87-4

Description: Famciclovir (INN) is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is also indicated for treatment of recurrent episodes of herpes simplex in HIV patients. It is a prodrug form of penciclovir with improved oral bioavailability.

Chemical Structure

CAS# 104227-87-4

Theoretical Analysis

MedKoo Cat#: 317861
Name: Famciclovir
CAS#: 104227-87-4
Chemical Formula: C14H19N5O4
Exact Mass: 321.1437
Molecular Weight: 321.3318
Elemental Analysis: C, 52.33; H, 5.96; N, 21.79; O, 19.92

Price and Availability

Size Price Availability Quantity
1.0g USD 290.0 2 weeks
2.0g USD 550.0 2 weeks
5.0g USD 850.0 2 weeks
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Synonym: Famciclovir, Famvir, BRL-42810

IUPAC/Chemical Name: [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate


InChi Code: InChI=1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 321.3318 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Mubareka S, Leung V, Aoki FY, Vinh DC. Famciclovir: a focus on efficacy and safety. Expert Opin Drug Saf. 2010 Jul;9(4):643-58. doi: 10.1517/14740338.2010.485189. Review. PubMed PMID: 20429777.

2: Aoki FY. The continuing evolution of antiviral therapy for recurrent genital herpes: 1-day patient-initiated treatment with famciclovir. Herpes. 2007 Dec;14(3):62-5. Review. PubMed PMID: 18371288.

3: Chacko M, Weinberg JM. Famciclovir for cutaneous herpesvirus infections: an update and review of new single-day dosing indications. Cutis. 2007 Jul;80(1):77-81. Review. PubMed PMID: 17725069.

4: Simpson D, Lyseng-Williamson KA. Famciclovir: a review of its use in herpes zoster and genital and orolabial herpes. Drugs. 2006;66(18):2397-416. Review. PubMed PMID: 17181386.

5: Vinh DC, Aoki FY. Famciclovir for the treatment of recurrent genital herpes: a clinical and pharmacological perspective. Expert Opin Pharmacother. 2006 Nov;7(16):2271-86. Review. PubMed PMID: 17059383.

6: Chakrabarty A, Tyring SK, Beutner K, Rauser M. Recent clinical experience with famciclovir--a "third generation" nucleoside prodrug. Antivir Chem Chemother. 2004 Sep;15(5):251-3. Review. PubMed PMID: 15535046.

7: Dekker CL, Prober CG. Pediatric uses of valacyclovir, penciclovir and famciclovir. Pediatr Infect Dis J. 2001 Nov;20(11):1079-81. Review. PubMed PMID: 11734715.

8: Shaw T, Locarnini SA. Preclinical aspects of lamivudine and famciclovir against hepatitis B virus. J Viral Hepat. 1999 Mar;6(2):89-106. Review. PubMed PMID: 10607220.

9: Sacks SL, Wilson B. Famciclovir/penciclovir. Adv Exp Med Biol. 1999;458:135-47. Review. PubMed PMID: 10549386.

10: Young CL. Famciclovir update. Chronic hepatitis B. Adv Exp Med Biol. 1999;458:23-7. Review. PubMed PMID: 10549376.

11: Jarvest RL, Sutton D, Vere Hodge RA. Famciclovir. Discovery and development of a novel antiherpesvirus agent. Pharm Biotechnol. 1998;11:313-43. Review. PubMed PMID: 9760686.

12: Tyring SK. Advances in the treatment of herpesvirus infection: the role of famciclovir. Clin Ther. 1998 Jul-Aug;20(4):661-70. Review. PubMed PMID: 9737826.

13: Faro S. A review of famciclovir in the management of genital herpes. Infect Dis Obstet Gynecol. 1998;6(1):38-43. Review. PubMed PMID: 9678146; PubMed Central PMCID: PMC1784770.

14: Sköldenberg B. [Antiviral therapy in herpes zoster. Famciclovir and valaciclovir are two good agents against shingles]. Lakartidningen. 1997 Dec 17;94(51-52):4881-4. Review. Swedish. PubMed PMID: 9454005.

15: Grose C, Wiedeman J. Generic acyclovir vs. famciclovir and valacyclovir. Pediatr Infect Dis J. 1997 Sep;16(9):838-41. Review. PubMed PMID: 9306476.

16: Guilarte López-Mañas J, Bellot García V, Martínez MA, Hernández Quero J. [Herpetic esophagitis treated with famciclovir in an immunocompetent patient]. Gastroenterol Hepatol. 1997 Aug-Sep;20(7):384-5. Review. Spanish. PubMed PMID: 9377241.

17: Stein GE. Pharmacology of new antiherpes agents: famciclovir and valacyclovir. J Am Pharm Assoc (Wash). 1997 Mar-Apr;NS37(2):157-63. Review. PubMed PMID: 9069689.

18: Bartholomeusz A, Groenen LC, Locarnini SA. Clinical experience with famciclovir against hepatitis B virus. Intervirology. 1997;40(5-6):337-42. Review. PubMed PMID: 9675638.

19: Luber AD, Flaherty JF Jr. Famciclovir for treatment of herpesvirus infections. Ann Pharmacother. 1996 Sep;30(9):978-85. Review. PubMed PMID: 8876860.

20: Gill KS, Wood MJ. The clinical pharmacokinetics of famciclovir. Clin Pharmacokinet. 1996 Jul;31(1):1-8. Review. PubMed PMID: 8827396.