WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317502
CAS#: 511-13-7 (HCl)
Description: Chlophedianol hydrochloride is a centrally acting cough suppressant used in the treatment of dry cough. Chlophediannol hydrochloride has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.
MedKoo Cat#: 317502
Name: Chlophedianol Hydrochloride
CAS#: 511-13-7 (HCl)
Chemical Formula: C17H21Cl2NO
Exact Mass:
Molecular Weight: 326.26
Elemental Analysis: C, 62.58; H, 6.49; Cl, 21.73; N, 4.29; O, 4.90
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 791-35-5 (free base) 511-13-7 (HCl)
Synonym: Chlophedianol Hydrochloride; 2-chloro-alpha-(2-dimethylaminoethyl)benzhydrol; Baltix; chlophedianol; chlophendianol hydrochloride; clofedanol; clofedanol hydrochloride;
IUPAC/Chemical Name: 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol;hydrochloride
InChi Key: XYGSFNHCFFAJPO-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H20ClNO.ClH/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18;/h3-11,20H,12-13H2,1-2H3;1H
SMILES Code: CN(C)CCC(C1=CC=CC=C1)(C2=CC=CC=C2Cl)O.Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 326.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Burrows GW, Evertts VL. High performance liquid chromatographic determination
of chlophedianol hydrochloride in "jung fei", a complex tablet formulation. J
Chromatogr Sci. 1985 Jan;23(1):37-8. PubMed PMID: 3968197.
2: Diwan J, Dhand R, Jindal SK, Malik SK, Sharma PL. A comparative randomized
double-blind clinical trial of isoaminile citrate and chlophedianol hydrochloride
as antitussive agents. Int J Clin Pharmacol Ther Toxicol. 1982 Aug;20(8):373-5.
PubMed PMID: 6749701.
3: Boyd EM, Boyd CE. Chlophedianol Hydrochloride: A New Antitussive Agent. Can
Med Assoc J. 1960 Dec 17;83(25):1298-301. PubMed PMID: 20326564; PubMed Central
PMCID: PMC1939025.
