Toreforant

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319560

CAS#: 952494-46-1

Description: Toreforant, aslo known as JNJ-38518168, is a potent Th1, TH17 and Th2 cell modulator. Toreforant is potential useful for treatment of diseases related to Antiasthmatics, Antihistamines, Antipruritics, Antipsoriatics, Antirheumatics.


Chemical Structure

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Toreforant
CAS# 952494-46-1

Theoretical Analysis

MedKoo Cat#: 319560
Name: Toreforant
CAS#: 952494-46-1
Chemical Formula: C23H32N6
Exact Mass: 392.2688
Molecular Weight: 392.55
Elemental Analysis: C, 70.37; H, 8.22; N, 21.41

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Synonym: JNJ-38518168; JNJ 38518168; JNJ38518168; Toreforant.

IUPAC/Chemical Name: 5-(4,6-dimethyl-1H-benzimidazol-2-yl)-4-methyl- N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine

InChi Key: FCRFVPZAXGJLPW-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H32N6/c1-15-12-16(2)21-20(13-15)27-22(28-21)19-14-25-23(26-17(19)3)24-9-5-6-18-7-10-29(4)11-8-18/h12-14,18H,5-11H2,1-4H3,(H,27,28)(H,24,25,26)

SMILES Code: CN1CCC(CCCNC2=NC=C(C3=NC4=C(C)C=C(C)C=C4N3)C(C)=N2)CC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 392.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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