Toreforant

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319560

CAS#: 952494-46-1

Description: Toreforant, aslo known as JNJ-38518168, is a potent Th1, TH17 and Th2 cell modulator. Toreforant is potential useful for treatment of diseases related to Antiasthmatics, Antihistamines, Antipruritics, Antipsoriatics, Antirheumatics.

Chemical Structure

Toreforant

CAS# 952494-46-1

Instruction

Theoretical Analysis

MedKoo Cat#: 319560
Name: Toreforant
CAS#: 952494-46-1
Chemical Formula: C23H32N6
Exact Mass: 392.2688
Molecular Weight: 392.55
Elemental Analysis: C, 70.37; H, 8.22; N, 21.41

Price and Availability

Size	Price	Availability	Quantity
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: JNJ-38518168; JNJ 38518168; JNJ38518168; Toreforant.

IUPAC/Chemical Name: 5-(4,6-dimethyl-1H-benzimidazol-2-yl)-4-methyl- N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine

InChi Key: FCRFVPZAXGJLPW-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H32N6/c1-15-12-16(2)21-20(13-15)27-22(28-21)19-14-25-23(26-17(19)3)24-9-5-6-18-7-10-29(4)11-8-18/h12-14,18H,5-11H2,1-4H3,(H,27,28)(H,24,25,26)

SMILES Code: CN1CCC(CCCNC2=NC=C(C3=NC4=C(C)C=C(C)C=C4N3)C(C)=N2)CC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Instruction:

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 392.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Your view history

Toreforant

1.0g / Ask price