WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319560
CAS#: 952494-46-1
Description: Toreforant, aslo known as JNJ-38518168, is a potent Th1, TH17 and Th2 cell modulator. Toreforant is potential useful for treatment of diseases related to Antiasthmatics, Antihistamines, Antipruritics, Antipsoriatics, Antirheumatics.
MedKoo Cat#: 319560
Name: Toreforant
CAS#: 952494-46-1
Chemical Formula: C23H32N6
Exact Mass: 392.2688
Molecular Weight: 392.55
Elemental Analysis: C, 70.37; H, 8.22; N, 21.41
Synonym: JNJ-38518168; JNJ 38518168; JNJ38518168; Toreforant.
IUPAC/Chemical Name: 5-(4,6-dimethyl-1H-benzimidazol-2-yl)-4-methyl- N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine
InChi Key: FCRFVPZAXGJLPW-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H32N6/c1-15-12-16(2)21-20(13-15)27-22(28-21)19-14-25-23(26-17(19)3)24-9-5-6-18-7-10-29(4)11-8-18/h12-14,18H,5-11H2,1-4H3,(H,27,28)(H,24,25,26)
SMILES Code: CN1CCC(CCCNC2=NC=C(C3=NC4=C(C)C=C(C)C=C4N3)C(C)=N2)CC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 392.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |