WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319555
Description: Ralinepag, also known as APD-811, is an orally available agonist of the prostacyclin (IP) receptor, is an investigational drug candidate internally discovered and developed by Arena and intended for the treatment of vasospastic diseases, such as Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, which elicits a potent vasodilation and inhibition of platelet aggregation when binding to this receptor.
MedKoo Cat#: 319555
Chemical Formula: C23H26ClNO5
Exact Mass: 431.15
Molecular Weight: 431.91
Elemental Analysis: C, 63.96; H, 6.07; Cl, 8.21; N, 3.24; O, 18.52
Synonym: APD-811; APD 811; APD811; Ralinepag
IUPAC/Chemical Name: 2-(((1r,4r)-4-((((4-chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetic acid
InChi Key: NPDKXVKJRHPDQT-IYARVYRRSA-N
InChi Code: O=C(COC[C@H]1CC[C@@H](CC1)COC(N(C2=CC=CC=C2)C3=CC=C(C=C3)Cl)=O)O
SMILES Code: O=C(O)COC[C@H]1CC[C@H](COC(N(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)=O)CC1