Ceftibuten Dihydrate
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MedKoo CAT#: 317452

CAS#: 118081-34-8 (hydrate)

Description: Ceftibuten dihydrate is the dihydrate form of ceftibuten. It is a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten inactivates penicillin-binding proteins located on the inner membrane of the bacterial cell wall. This results in the weakening of the bacterial cell wall and causes cell lysis.


Chemical Structure

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Ceftibuten Dihydrate
CAS# 118081-34-8 (hydrate)

Theoretical Analysis

MedKoo Cat#: 317452
Name: Ceftibuten Dihydrate
CAS#: 118081-34-8 (hydrate)
Chemical Formula: C15H18N4O8S2
Exact Mass:
Molecular Weight: 446.46
Elemental Analysis: C, 40.35; H, 4.06; N, 12.55; O, 28.67; S, 14.36

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Related CAS #: 97519-39-6 (free)   118081-34-8 (hydrate)    

Synonym: Ceftibuten Dihydrate; UNII-62F4443RWP; Seftem; ceftibuten.2H2O; Seftem (TN); Cedax (TN); AC1NQZPM; Ceftibuten (dihydrate); CEFTIBUTEN 2-HYDRATE; Ceftibuten hydrate (JP16); SCHEMBL159144; CHEBI:34618; HY-B0698A; 62F4443RWP; AKOS025149353; AN-6406; HE068843; HE299817; O441; FT-0664440; D02121; A803878; I06-1263

IUPAC/Chemical Name: (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;dihydrate

InChi Key: SSWTVBYDDFPFAF-ODPSPGRDSA-N

InChi Code: InChI=1S/C15H14N4O6S2.2H2O/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19;;/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25);2*1H2/b6-1+;;

SMILES Code: C1C=C(N2C(S1)C(C2=O)NC(=O)C(=CCC(=O)O)C3=CSC(=N3)N)C(=O)O.O.O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 446.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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