WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317184
CAS#: 88150-42-9 (free base)
Description: Amlodipine (as besylate, mesylate or maleate) is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.
MedKoo Cat#: 317184
Name: Amlodipine
CAS#: 88150-42-9 (free base)
Chemical Formula: C20H25ClN2O5
Exact Mass: 408.1452
Molecular Weight: 408.88
Elemental Analysis: C, 58.75; H, 6.16; Cl, 8.67; N, 6.85; O, 19.57
Amlodipine, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Related CAS #: 88150-47-4 (maleate) 88150-42-9 (free base) 111470-99-6 (besylate)
Synonym: Amlodis; Norvasc; Amlocard; Coroval; Amlodipine Besylate; Amlodipine Maleate; Amlodipine Maleate
IUPAC/Chemical Name: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key: HTIQEAQVCYTUBX-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
SMILES Code: O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Cl)OCC
The following data is based on the product molecular weight 408.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Gottwald-Hostalek U, Sun N, Barho C, Hildemann S. Management of Hypertension With a Fixed-Dose (Single-Pill) Combination of Bisoprolol and Amlodipine. Clin Pharmacol Drug Dev. 2017 Jan;6(1):9-18. doi: 10.1002/cpdd.309. Epub 2016 Oct 26. PubMed PMID: 27653022.
2: van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. Review. PubMed PMID: 9156957.
Related:
88150-42-9 (Amlodipine)
111470-99-6 (Amlodipine besylate)
88150-47-4(Amlodipine maleate)