Azatadine Maleate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317301

CAS#: 3978-86-7

Description: Azatadine dimaleate is an antihistamine and anticholinergic inhibitor. It is used for treating allergic rhinitis and chronic urticaria.

Chemical Structure

Azatadine Maleate
CAS# 3978-86-7

Theoretical Analysis

MedKoo Cat#: 317301
Name: Azatadine Maleate
CAS#: 3978-86-7
Chemical Formula: C28H30N2O8
Exact Mass: 522.2
Molecular Weight: 522.55
Elemental Analysis: C, 64.36; H, 5.79; N, 5.36; O, 24.49

Price and Availability

Size Price Availability Quantity
20.0mg USD 210.0 2 Weeks
50.0mg USD 280.0 2 Weeks
250.0mg USD 380.0 2 Weeks
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Synonym: Azatadine Maleate; azatadine; azatadine maleate; Idulamine; Idulian; Juste brand of azatadine maleate; Key brand of azatadine maleate; Lergocil; Optimine; Schering brand of azatadine maleate; Schering-Plough brand of azatadine maleate; Zadine

IUPAC/Chemical Name: 6,11-Dihydro-11-(1-methylpiperidin-4-ylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine dimaleate


InChi Code: InChI=1S/C20H22N2.2C4H4O4/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19;2*5-3(6)1-2-4(7)8/h2-7,12H,8-11,13-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

SMILES Code: CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C4\2.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 522.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Keene AT, Chard CL, Daniels VG. General practitioner surveillance of azatadine
maleate/pseudoephedrine sulphate ('Congesteze') for the treatment of upper
respiratory tract congestion. Pharmatherapeutica. 1984;3(10):657-62. PubMed PMID:

2: Luscombe DK, Nicholls PJ, Parish PA. Comparison of the effects of azatadine
maleate and terfenadine on human performance. Pharmatherapeutica.
1983;3(6):370-5. PubMed PMID: 6137832.

3: Kaminszczik I, Barbon L. Relieving symptoms of upper respiratory allergies and
the common cold: azatadine maleate/pseudoephedrine sulfate syrup versus placebo.
J Int Med Res. 1983;11(2):101-7. PubMed PMID: 6133802.

4: Wilson JD, Hillas JL, Somerfield SD. Azatadine maleate (Zadine): evaluation in
the management of allergic rhinitis. N Z Med J. 1981 Aug 12;94(689):79-81. PubMed
PMID: 7024868.

5: Hillas JL, Somerfield SD, Wilson JD, Aman MG. Azatadine maleate in perennial
allergic rhinitis: effects on clinical symptoms and choice reaction time. Br J
Clin Pharmacol. 1980 Dec;10(6):573-7. PubMed PMID: 7008821; PubMed Central PMCID:

6: Zubizaretta J. Azatadine maleate/pseudoephedrine sulfate repetabs versus
placebo in the treatment of severe perennial allergic rhinitis. J Int Med Res.
1980;8(6):395-9. PubMed PMID: 6108263.

7: Tarasido JC. Azatadine maleate/pseudoephedrine sulfate repetabs versus placebo
in the treatment of severe seasonal allergic rhinitis. J Int Med Res.
1980;8(6):391-4. PubMed PMID: 6108262.

8: Biehl B. Effects of azatadine maleate on subjective appraisal and psychomotor
functions relevant to driving performance. Curr Med Res Opin. 1979;6(1):62-9.
PubMed PMID: 37045.