WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 522511
Description: SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
MedKoo Cat#: 522511
Chemical Formula: C18H23F2N5O4S2
Exact Mass: 475.11595
Molecular Weight: 475.52981
Elemental Analysis: C, 45.46; H, 4.88; F, 7.99; N, 14.73; O, 13.46; S, 13.48
SRT3109, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received.
Synonym: SRT3109; SRT-3109; SRT 3109.
IUPAC/Chemical Name: N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide
InChi Key: QVKPEMXUBULFBM-RISCZKNCSA-N
InChi Code: InChI=1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3,(H2,21,22,23,24)/t11-,14+/m1/s1
SMILES Code: C[C@H]([C@H](CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3
The following data is based on the product molecular weight 475.52981 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|