WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 318857
Description: Thiabendazole is a fungicide and parasiticide. Tiabendazole works by inhibition of the mitochondrial, helminth-specific enzyme, fumarate reductase, with possible interaction with endogenous quinone. Tiabendazole serves to block angiogenesis in both frog embryos and human cells. It has also been shown to serve as a vascular disrupting agent to reduce newly established blood vessels. Tiabendazole has been shown to effectively do this in certain cancer cells.
MedKoo Cat#: 318857
Chemical Formula: C10H7N3S
Exact Mass: 201.03607
Molecular Weight: 201.247
Elemental Analysis: C, 59.68; H, 3.51; N, 20.88; S, 15.93
Thiabendazole, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Synonym: TBZ; Thibendole; Thiabendazol; Thiabendazole. Trade names Mintezol, Tresaderm, Arbotec; Mintesol; Omnizole.
IUPAC/Chemical Name: 4-(1H-1,3-benzodiazol-2-yl)-1,3-thiazole
InChi Key: WJCNZQLZVWNLKY-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
SMILES Code: C1(C2=NC3=CC=CC=C3N2)=CSC=N1
The following data is based on the product molecular weight 201.247 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Lönngren V, Holst E, Ljunggren B. Larval papulonodular dermatitis treated with
topical tiabendazole. Lancet Infect Dis. 2010 Jul;10(7):504. doi:
10.1016/S1473-3099(10)70104-3. PubMed PMID: 20610333.
2: Baliharová V, Skálová L, Maas RF, De Vrieze G, Bull S, Fink-Gremmels J. The
effects of mebendazole on P4501A activity in rat hepatocytes and HepG2 cells.
Comparison with tiabendazole and omeprazole. J Pharm Pharmacol. 2003
Jun;55(6):773-81. PubMed PMID: 12841937.
3: Fourestié V, Bougnoux ME, Ancelle T, Liance M, Roudot-Thoraval F, Naga H,
Pairon-Pennachioni M, Rauss A, Lejonc JL. Randomized trial of albendazole versus
tiabendazole plus flubendazole during an outbreak of human trichinellosis.
Parasitol Res. 1988;75(1):36-41. PubMed PMID: 3060872.