WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317369
Description: Carbenicillin is a bactericidal antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It was discovered by scientists at Beecham and marketed as Pyopen. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more resistant than ampicillin to degradation. Carbenicillin is also more stable at lower pH than ampicillin.
MedKoo Cat#: 317369
Chemical Formula: C17H18N2O6S
Exact Mass: 378.08856
Molecular Weight: 378.4
Elemental Analysis: C, 53.96; H, 4.79; N, 7.40; O, 25.37; S, 8.47
Carbenicillin, purity > 98% is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Synonym: Carbenicillin, Anabactyl, Carbapen
IUPAC/Chemical Name: (2S,5R,6R)-6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChi Key: FPPNZSSZRUTDAP-UWFZAAFLSA-N
InChi Code: InChI=1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1
SMILES Code: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C(O)=O)C3=CC=CC=C3)=O)N1C2=O)O
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|Soluble in DMSO, not in water||100.0|
The following data is based on the product molecular weight 378.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Liu X, Li Y, Guo Y, Zeng Z, Li B, Wood TK, Cai X, Wang X. Physiological
Function of Rac Prophage During Biofilm Formation and Regulation of Rac Excision
in Escherichia coli K-12. Sci Rep. 2015 Nov 4;5:16074. doi: 10.1038/srep16074.
PubMed PMID: 26530864.
2: Wang YT, Cheng TL. Refined Models of New Delhi metallo-beta-lactamase-1 with
Inhibitors: An QM/MM Modeling Study. J Biomol Struct Dyn. 2015 Oct 21:1-41. [Epub
ahead of print] PubMed PMID: 26488313.
3: El-Zahry MR, Refaat IH, Mohamed HA, Rosenberg E, Lendl B. Utility of surface
enhanced Raman spectroscopy (SERS) for elucidation and simultaneous determination of some penicillins and penicilloic acid using hydroxylamine silver
nanoparticles. Talanta. 2015 Nov 1;144:710-6. doi: 10.1016/j.talanta.2015.07.015.
Epub 2015 Jul 10. PubMed PMID: 26452881.