Carbachol
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317367

CAS#: 51-83-2

Description: Carbachol is a cholinomimetic drug that binds and activates the acetylcholine receptor. Thus it is classified as a cholinergic agonist. It is primarily used for various ophthalmic purposes, such as for treating glaucoma, or for use during ophthalmic surgery. It is generally administered as an ophthalmic solution (i.e. eyedrops).


Chemical Structure

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Carbachol
CAS# 51-83-2

Theoretical Analysis

MedKoo Cat#: 317367
Name: Carbachol
CAS#: 51-83-2
Chemical Formula: C6H15ClN2O2
Exact Mass: 182.08221
Molecular Weight: 182.65
Elemental Analysis: C, 39.46; H, 8.28; Cl, 19.41; N, 15.34; O, 17.52

Price and Availability

Size Price Availability Quantity
1.0g USD 150.0 2 Weeks
2.0g USD 190.0 2 Weeks
5.0g USD 250.0 2 Weeks
10.0g USD 450.0 2 Weeks
25.0g USD 650.0 2 Weeks
50.0g USD 950.0 2 Weeks
100.0g USD 1650.0 2 Weeks
200.0g USD 2650.0 2 Weeks
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Synonym: Carbastat, Carboptic, Isopto Carbachol, Miostat, Carbamylcholine

IUPAC/Chemical Name: 2-carbamoyloxyethyl(trimethyl)azanium;chloride

InChi Key: AIXAANGOTKPUOY-UHFFFAOYSA-N

InChi Code: InChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

SMILES Code: C[N+](C)(CCOC(N)=O)C.[Cl-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 182.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Fornai M, Pellegrini C, Antonioli L, Segnani C, Ippolito C, Barocelli E,
Ballabeni V, Vegezzi G, Al Harraq Z, Blandini F, Levandis G, Cerri S, Blandizzi
C, Bernardini N, Colucci R. Enteric dysfunctions in experimental Parkinson's
disease: alterations of excitatory cholinergic neurotransmission regulating
colonic motility in rats. J Pharmacol Exp Ther. 2015 Nov 18. pii:
jpet.115.228510. [Epub ahead of print] PubMed PMID: 26582732.

2: Sakai H, Sato K, Yuki K, Chiba Y, Narita M. Denatonium and
6-n-propyl-2-thiouracil, agonists of bitter taste receptor, inhibit contraction
of various types of smooth muscles in the rat and mouse. Biol Pharm Bull. 2015
Nov 14. [Epub ahead of print] PubMed PMID: 26567724.