WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317356
CAS#: 18010-40-7 (HCl)
Description: Bupivacaine, is a medication used to freeze tissue in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours. Bupivacaine binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Without depolarization, no initiation or conduction of a pain signal can occur.
MedKoo Cat#: 317356
Name: Bupivacaine HCl
CAS#: 18010-40-7 (HCl)
Chemical Formula: C18H29ClN2O
Exact Mass: 288.22016
Molecular Weight: 324.893
Elemental Analysis: C, 66.54; H, 9.00; Cl, 10.91; N, 8.62; O, 4.92
Bupivacaine HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Related CAS #: 18010-40-7 (HCl) 2180-92-9 (free base)
Synonym: Bupivacaine, Marcaine; AH-250; HSDB 7790; SKY 0402; SKY0402, Win 11318; AH 250; AH250; HSDB7790; HSDB-7790; SKY-0402; Win-11318; Win11318
IUPAC/Chemical Name: 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride
InChi Key: SIEYLFHKZGLBNX-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H
SMILES Code: O=C(C1N(CCCC)CCCC1)NC2=C(C)C=CC=C2C
The following data is based on the product molecular weight 324.893 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Li H, Wang B, Wang F, Xu Z, Zhou N, Wang X, Wang K. Effects of epidural
analgesia with different concentrations of bupivacaine plus fentanyl on pain in
patients undergoing thoracic surgery. Int J Clin Exp Med. 2015 Aug
15;8(8):14123-6. eCollection 2015. PubMed PMID: 26550381; PubMed Central PMCID:
2: Lin S, Hua J, Xu B, Yang T, He Z, Xu C, Meng H, Zhou B, Song Z. Comparison of
bupivacaine and parecoxib for postoperative pain relief after laparoscopic
cholecystectomy: a randomized controlled trial. Int J Clin Exp Med. 2015 Aug
15;8(8):13824-9. eCollection 2015. PubMed PMID: 26550332; PubMed Central PMCID: