Brompheniramine maleate
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MedKoo CAT#: 317353

CAS#: 980-71-2 (maleate)

Description: Brompheniramine, commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine. Brompheniramine works by acting as an antagonist of histamine H1 receptors. It also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine.


Chemical Structure

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Brompheniramine maleate
CAS# 980-71-2 (maleate)

Theoretical Analysis

MedKoo Cat#: 317353
Name: Brompheniramine maleate
CAS#: 980-71-2 (maleate)
Chemical Formula: C20H23BrN2O4
Exact Mass: 318.07316
Molecular Weight: 435.318
Elemental Analysis: C, 55.18; H, 5.33; Br, 18.36; N, 6.44; O, 14.70

Size Price Shipping out time Quantity
1g USD 90 2 Weeks
2g USD 150 2 Weeks
5g USD 300 2 Weeks
10g USD 450 2 Weeks
25g USD 650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-01. Prices are subject to change without notice.

Brompheniramine maleate, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Related CAS #: 980-71-2 (maleate)   86-22-6 (free base).  

Synonym: Brompheniramine, Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane

IUPAC/Chemical Name: 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine maleate

InChi Key: SRGKFVAASLQVBO-BTJKTKAUSA-N

InChi Code: InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code: CN(C)CCC(C1=CC=C(Br)C=C1)C2=NC=CC=C2.O=C(O)/C=C\C(O)=O

Appearance:
White solid powder.

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 435.318 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Nosáľ R, Jančinová V, Drábiková K, Perečko T. Molecular pharmacology of
antihistamines in inhibition of oxidative burst of professional phagocytes. Gen
Physiol Biophys. 2015 Apr;34(2):209-16. doi: 10.4149/gpb_2014040. Epub 2015 Mar
2. PubMed PMID: 25730898.

2: Liu YP, Huang TS, Tung CS, Lin CC. Effects of atomoxetine on attention and
impulsivity in the five-choice serial reaction time task in rats with lesions of
dorsal noradrenergic ascending bundle. Prog Neuropsychopharmacol Biol Psychiatry.
2015 Jan 2;56:81-90. doi: 10.1016/j.pnpbp.2014.08.007. Epub 2014 Aug 21. PubMed
PMID: 25151304.