Brompheniramine maleate

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MedKoo CAT#: 317353

CAS#: 980-71-2 (maleate)

Description: Brompheniramine, commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. It is a first-generation antihistamine. Brompheniramine works by acting as an antagonist of histamine H1 receptors. It also functions as a moderately effective anticholinergic agent, and is likely an antimuscarinic agent similar to other common antihistamines such as diphenhydramine.

Chemical Structure

Brompheniramine maleate
CAS# 980-71-2 (maleate)

Theoretical Analysis

MedKoo Cat#: 317353
Name: Brompheniramine maleate
CAS#: 980-71-2 (maleate)
Chemical Formula: C20H23BrN2O4
Exact Mass: 318.07316
Molecular Weight: 435.318
Elemental Analysis: C, 55.18; H, 5.33; Br, 18.36; N, 6.44; O, 14.70

Price and Availability

Size Price Availability Quantity
1.0g USD 90.0 2 Weeks
2.0g USD 150.0 2 Weeks
5.0g USD 300.0 2 Weeks
10.0g USD 450.0 2 Weeks
25.0g USD 650.0 2 Weeks
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Related CAS #: 980-71-2 (maleate)   86-22-6 (free base).  

Synonym: Brompheniramine, Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane

IUPAC/Chemical Name: 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine maleate


InChi Code: InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-


Appearance: White solid powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 435.318 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Nosáľ R, Jančinová V, Drábiková K, Perečko T. Molecular pharmacology of
antihistamines in inhibition of oxidative burst of professional phagocytes. Gen
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2: Liu YP, Huang TS, Tung CS, Lin CC. Effects of atomoxetine on attention and
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dorsal noradrenergic ascending bundle. Prog Neuropsychopharmacol Biol Psychiatry.
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PMID: 25151304.