Albendazole
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 317162

CAS#: 54965-21-8

Description: Albendazole is an oral medication used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among others. Albendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. Albendazole came into use in 1971. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.


Chemical Structure

img
Albendazole
CAS# 54965-21-8

Theoretical Analysis

MedKoo Cat#: 317162
Name: Albendazole
CAS#: 54965-21-8
Chemical Formula: C12H15N3O2S
Exact Mass: 265.0885
Molecular Weight: 265.33
Elemental Analysis: C, 54.32; H, 5.70; N, 15.84; O, 12.06; S, 12.08

Price and Availability

Size Price Availability Quantity
2.0g USD 150.0 2 Weeks
5.0g USD 250.0 2 Weeks
10.0g USD 350.0 2 Weeks
20.0g USD 550.0 2 Weeks
50.0g USD 650.0 2 Weeks
Bulk inquiry

Synonym: Albendazole; Eskazole; Zentel; Albenza; Valbazen

IUPAC/Chemical Name: methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate

InChi Key: HXHWSAZORRCQMX-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

SMILES Code: CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 265.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: PLOS Neglected Tropical Diseases Staff. Correction: Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice. PLoS Negl Trop Dis. 2015 Oct 29;9(10):e0004181. doi: 10.1371/journal.pntd.0004181. eCollection 2015 Oct. PubMed PMID: 26512896.

2: Aboagye-Antwi F, Kwansa-Bentum B, Dadzie SK, Ahorlu CK, Appawu MA, Gyapong J, Wilson MD, Boakye DA. Transmission indices and microfilariae prevalence in human population prior to mass drug administration with ivermectin and albendazole in the Gomoa District of Ghana. Parasit Vectors. 2015 Oct 26;8(1):562. doi: 10.1186/s13071-015-1105-x. PubMed PMID: 26503363; PubMed Central PMCID: PMC4624376.

3: Thomsen EK, Sanuku N, Baea M, Satofan S, Maki E, Lombore B, Schmidt MS, Siba PM, Weil GJ, Kazura JW, Fleckenstein LL, King CL. Efficacy, Safety, and Pharmacokinetics of Co-Administered Diethylcarbamazine, Albendazole, and Ivermectin for the Treatment of Bancroftian Filariasis. Clin Infect Dis. 2015 Oct 20. pii: civ882. [Epub ahead of print] PubMed PMID: 26486704.

4: Escobedo AA, Ballesteros J, González-Fraile E, Almirall P. A meta-analysis of the efficacy of albendazole compared with tinidazole as treatments for Giardia infections in children. Acta Trop. 2015 Oct 14. pii: S0001-706X(15)30121-2. doi: 10.1016/j.actatropica.2015.09.023. [Epub ahead of print] Review. PubMed PMID: 26476393.

5: Romo ML, Wyka K, Carpio A, Leslie D, Andrews H, Bagiella E, Hauser WA, Kelvin EA; Ecuadorian Neurocysticercosis Group. The effect of albendazole treatment on seizure outcomes in patients with symptomatic neurocysticercosis. Trans R Soc Trop Med Hyg. 2015 Nov;109(11):738-46. doi: 10.1093/trstmh/trv078. Epub 2015 Oct 3. PubMed PMID: 26433183.

6: Ortonobes Roig S, López García B, Solano Luque MF, Ferrández Quirante O. [Haematological toxicity during treatment with albendazole]. Enferm Infecc Microbiol Clin. 2015 Sep 29. pii: S0213-005X(15)00288-8. doi: 10.1016/j.eimc.2015.07.013. [Epub ahead of print] Spanish. PubMed PMID: 26432766.

7: Pensel PE, Ullio Gamboa G, Fabbri J, Ceballos L, Sanchez Bruni S, Alvarez LI, Allemandi D, Benoit JP, Palma SD, Elissondo MC. Cystic echinococcosis therapy: Albendazole-loaded lipid nanocapsules enhance the oral bioavailability and efficacy in experimentally infected mice. Acta Trop. 2015 Sep 26;152:185-194. doi: 10.1016/j.actatropica.2015.09.016. [Epub ahead of print] PubMed PMID: 26409727.

8: Chami GF, Kontoleon AA, Bulte E, Fenwick A, Kabatereine NB, Tukahebwa EM, Dunne DW. Profiling Nonrecipients of Mass Drug Administration for Schistosomiasis and Hookworm Infections: A Comprehensive Analysis of Praziquantel and Albendazole Coverage in Community-Directed Treatment in Uganda. Clin Infect Dis. 2015 Sep 25. pii: civ829. [Epub ahead of print] PubMed PMID: 26409064.

9: Belew S, Getachew M, Suleman S, Mohammed T, Deti H, D'Hondt M, Wynendaele E, Mekonnen Z, Vercruysse J, Duchateau L, De Spiegeleer B, Levecke B. Assessment of Efficacy and Quality of Two Albendazole Brands Commonly Used against Soil-Transmitted Helminth Infections in School Children in Jimma Town, Ethiopia. PLoS Negl Trop Dis. 2015 Sep 25;9(9):e0004057. doi: 10.1371/journal.pntd.0004057. eCollection 2015 Sep. PubMed PMID: 26406600; PubMed Central PMCID: PMC4583991.

10: Abulaihaiti M, Wu XW, Qiao L, Lv HL, Zhang HW, Aduwayi N, Wang YJ, Wang XC, Peng XY. Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in Mice. PLoS Negl Trop Dis. 2015 Sep 9;9(9):e0003950. doi: 10.1371/journal.pntd.0003950. eCollection 2015 Sep. PubMed PMID: 26352932; PubMed Central PMCID: PMC4564103.