WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317254
CAS#: 198904-31-3 (free base)
Description: Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class. It is sold under the trade name Reyataz. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus. Atazanavir is distinguished from other PIs in that it can be given once-daily and has lesser effects on the patient's lipid profile. Like other protease inhibitors, it is used only in combination with other HIV medications.
MedKoo Cat#: 317254
Name: Atazanavir
CAS#: 198904-31-3 (free base)
Chemical Formula: C38H52N6O7
Exact Mass: 704.38975
Molecular Weight: 704.86
Elemental Analysis: C, 64.75; H, 7.44; N, 11.92; O, 15.89
Atazanavir, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Related CAS #: 229975-97-7 (sulfate) 198904-31-3 (free base)
Synonym: Atazanavir; 198904-31-3; Latazanavir; Zrivada; BMS-232632; Reyataz;
IUPAC/Chemical Name: methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
InChi Key: AXRYRYVKAWYZBR-UHFFFAOYSA-N
InChi Code: InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)
SMILES Code: CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC
The following data is based on the product molecular weight 704.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Chitturi SR, Somannavar YS, Peruri BG, Nallapati S, Sharma HK, Budidet SR, Handa VK, Vurimindi HB. Gradient RP-HPLC method for the determination of potential impurities in atazanavir sulfate. J Pharm Biomed Anal. 2011 Apr 28;55(1):31-47. doi: 10.1016/j.jpba.2011.01.002. Epub 2011 Jan 19. PubMed PMID: 21316175.
Related:
198904-31-3(Atazanavir)
229975-97-7(Atazanavir sulfate).
